Selective immunocapture reveals neoplastic human mast cells secrete distinct microvesicle‐ and exosome‐like populations of KIT‐containing extracellular vesicles

Activating mutations in the receptor KIT promote the dysregulated proliferation of human mast cells (huMCs). The resulting neoplastic huMCs secrete extracellular vesicles (EVs) that can transfer oncogenic KIT among other cargo into recipient cells. Despite potential contributions to diseases, KIT‐co...

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Detalles Bibliográficos
Autores principales: Pfeiffer, Annika, Petersen, Jennifer D., Falduto, Guido H., Anderson, David Eric, Zimmerberg, Joshua, Metcalfe, Dean D., Olivera, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838129/
https://www.ncbi.nlm.nih.gov/pubmed/36239715
http://dx.doi.org/10.1002/jev2.12272

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