The relationship among amyloid-β deposition, sphingomyelin level, and the expression and function of P-glycoprotein in Alzheimer’s disease pathological process

In Alzheimer’s disease, the transporter P-glycoprotein is responsible for the clearance of amyloid-β in the brain. Amyloid-β correlates with the sphingomyelin metabolism, and sphingomyelin participates in the regulation of P-glycoprotein. The amyloid cascade hypothesis describes amyloid-β as the cen...

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Detalles Bibliográficos
Autores principales: Xing, Zi-Kang, Du, Li-Sha, Fang, Xin, Liang, Heng, Zhang, Sheng-Nan, Shi, Lei, Kuang, Chun-Xiang, Han, Tian-Xiong, Yang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838140/
https://www.ncbi.nlm.nih.gov/pubmed/36453415
http://dx.doi.org/10.4103/1673-5374.358607

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