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Gut microbial metabolites lower blood pressure in patients with hypertension
Supplementation with the gut microbial-derived metabolites acetate and butyrate has been shown to lower blood pressure in experimental models of hypertension. However, the translational potential of these metabolites has been unexplored. We provide clinical evidence that acetate and butyrate lower b...
| Formato: | Online Artículo Texto |
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| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838414/ https://www.ncbi.nlm.nih.gov/pubmed/36688212 http://dx.doi.org/10.1038/s44161-022-00204-8 |
| _version_ | 1784869280919060480 |
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| collection | PubMed |
| description | Supplementation with the gut microbial-derived metabolites acetate and butyrate has been shown to lower blood pressure in experimental models of hypertension. However, the translational potential of these metabolites has been unexplored. We provide clinical evidence that acetate and butyrate lower blood pressure in untreated patients with hypertension. |
| format | Online Article Text |
| id | pubmed-9838414 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2023 |
| publisher | Nature Publishing Group UK |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-98384142023-01-17 Gut microbial metabolites lower blood pressure in patients with hypertension Nat Cardiovasc Res Research Briefing Supplementation with the gut microbial-derived metabolites acetate and butyrate has been shown to lower blood pressure in experimental models of hypertension. However, the translational potential of these metabolites has been unexplored. We provide clinical evidence that acetate and butyrate lower blood pressure in untreated patients with hypertension. Nature Publishing Group UK 2023-01-12 2023 /pmc/articles/PMC9838414/ /pubmed/36688212 http://dx.doi.org/10.1038/s44161-022-00204-8 Text en © Springer Nature Limited 2023 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
| spellingShingle | Research Briefing Gut microbial metabolites lower blood pressure in patients with hypertension |
| title | Gut microbial metabolites lower blood pressure in patients with hypertension |
| title_full | Gut microbial metabolites lower blood pressure in patients with hypertension |
| title_fullStr | Gut microbial metabolites lower blood pressure in patients with hypertension |
| title_full_unstemmed | Gut microbial metabolites lower blood pressure in patients with hypertension |
| title_short | Gut microbial metabolites lower blood pressure in patients with hypertension |
| title_sort | gut microbial metabolites lower blood pressure in patients with hypertension |
| topic | Research Briefing |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838414/ https://www.ncbi.nlm.nih.gov/pubmed/36688212 http://dx.doi.org/10.1038/s44161-022-00204-8 |