Assessing and advancing the safety of CRISPR-Cas tools: from DNA to RNA editing

CRISPR-Cas gene editing has revolutionized experimental molecular biology over the past decade and holds great promise for the treatment of human genetic diseases. Here we review the development of CRISPR-Cas9/Cas12/Cas13 nucleases, DNA base editors, prime editors, and RNA base editors, focusing on...

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Detalles Bibliográficos
Autores principales: Tao, Jianli, Bauer, Daniel E., Chiarle, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838544/
https://www.ncbi.nlm.nih.gov/pubmed/36639728
http://dx.doi.org/10.1038/s41467-023-35886-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838544/
https://www.ncbi.nlm.nih.gov/pubmed/36639728
http://dx.doi.org/10.1038/s41467-023-35886-6

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