Aquaporin5 Deficiency Aggravates ROS/NLRP3 Inflammasome-Mediated Pyroptosis in the Lacrimal Glands

PURPOSE: The pathogenesis of the lacrimal glands (LGs) is facilitated by inflammation mediated by the NACHT, LRR, and NLRP3 inflammasomes in dry eye disease. This research aimed to explore the protective effects of Aquaporin 5 (AQP5) on LGs by inhibiting reactive oxygen species (ROS) and the NLRP3 i...

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Detalles Bibliográficos
Autores principales: Cao, Xin, Di, Guohu, Bai, Ying, Zhang, Kaier, Wang, Yihui, Zhao, Hui, Wang, Dianqiang, Chen, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Biochemistry and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838588/
https://www.ncbi.nlm.nih.gov/pubmed/36626177
http://dx.doi.org/10.1167/iovs.64.1.4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838588/
https://www.ncbi.nlm.nih.gov/pubmed/36626177
http://dx.doi.org/10.1167/iovs.64.1.4

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