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Hypoxia Increases the Potential for Neutrophil-mediated Endothelial Damage in Chronic Obstructive Pulmonary Disease

RATIONALE: Patients with chronic obstructive pulmonary disease (COPD) experience excess cardiovascular morbidity and mortality, and exacerbations further increase the risk of such events. COPD is associated with persistent blood and airway neutrophilia and systemic and tissue hypoxia. Hypoxia augmen...

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Detalles Bibliográficos
Autores principales: Lodge, Katharine M., Vassallo, Arlette, Liu, Bin, Long, Merete, Tong, Zhen, Newby, Paul R., Agha-Jaffar, Danya, Paschalaki, Koralia, Green, Clara E., Belchamber, Kylie B. R., Ridger, Victoria C., Stockley, Robert A., Sapey, Elizabeth, Summers, Charlotte, Cowburn, Andrew S., Chilvers, Edwin R., Li, Wei, Condliffe, Alison M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Thoracic Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9838628/
https://www.ncbi.nlm.nih.gov/pubmed/35044899
http://dx.doi.org/10.1164/rccm.202006-2467OC