Innate Immunity and Phenoptosis

The hypothesis is proposed that activation of innate immunity is the primary mechanism of phenoptosis (programmed death of an organism). In support of the hypothesis, we discuss (i) the data on active release of signaling molecules from the cell producing excessive inflammation; (ii) the data on con...

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Detalles Bibliográficos
Autores principales: Chernyak, Boris V., Lyamzaev, Konstantin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pleiades Publishing 2023
Materias:
Hypothesis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839199/
https://www.ncbi.nlm.nih.gov/pubmed/36717452
http://dx.doi.org/10.1134/S0006297922120185
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author Chernyak, Boris V.
Lyamzaev, Konstantin G.
author_facet Chernyak, Boris V.
Lyamzaev, Konstantin G.
author_sort Chernyak, Boris V.
collection PubMed
description The hypothesis is proposed that activation of innate immunity is the primary mechanism of phenoptosis (programmed death of an organism). In support of the hypothesis, we discuss (i) the data on active release of signaling molecules from the cell producing excessive inflammation; (ii) the data on contribution of mitochondrial production of reactive oxygen species to immune response.
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spelling pubmed-98391992023-01-17 Innate Immunity and Phenoptosis Chernyak, Boris V. Lyamzaev, Konstantin G. Biochemistry (Mosc) Hypothesis The hypothesis is proposed that activation of innate immunity is the primary mechanism of phenoptosis (programmed death of an organism). In support of the hypothesis, we discuss (i) the data on active release of signaling molecules from the cell producing excessive inflammation; (ii) the data on contribution of mitochondrial production of reactive oxygen species to immune response. Pleiades Publishing 2023-01-13 2022 /pmc/articles/PMC9839199/ /pubmed/36717452 http://dx.doi.org/10.1134/S0006297922120185 Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open access.This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution, and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit https://creativecommons.org/licenses/by/4.0/.
spellingShingle Hypothesis
Chernyak, Boris V.
Lyamzaev, Konstantin G.
Innate Immunity and Phenoptosis
title Innate Immunity and Phenoptosis
title_full Innate Immunity and Phenoptosis
title_fullStr Innate Immunity and Phenoptosis
title_full_unstemmed Innate Immunity and Phenoptosis
title_short Innate Immunity and Phenoptosis
title_sort innate immunity and phenoptosis
topic Hypothesis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839199/
https://www.ncbi.nlm.nih.gov/pubmed/36717452
http://dx.doi.org/10.1134/S0006297922120185
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