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Influence of extracellular matrix composition on tumour cell behaviour in a biomimetic in vitro model for hepatocellular carcinoma

The tumor micro-environment (TME) of hepatocellular carcinoma (HCC) consists out of cirrhotic liver tissue and is characterized by an extensive deposition of extracellular matrix proteins (ECM). The evolution from a reversible fibrotic state to end-stage of liver disease, namely cirrhosis, is charac...

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Detalles Bibliográficos
Autores principales: Calitz, Carlemi, Rosenquist, Jenny, Degerstedt, Oliver, Khaled, Jaafar, Kopsida, Maria, Fryknäs, Mårten, Lennernäs, Hans, Samanta, Ayan, Heindryckx, Femke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839216/
https://www.ncbi.nlm.nih.gov/pubmed/36639512
http://dx.doi.org/10.1038/s41598-023-27997-3

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