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Influence of extracellular matrix composition on tumour cell behaviour in a biomimetic in vitro model for hepatocellular carcinoma
The tumor micro-environment (TME) of hepatocellular carcinoma (HCC) consists out of cirrhotic liver tissue and is characterized by an extensive deposition of extracellular matrix proteins (ECM). The evolution from a reversible fibrotic state to end-stage of liver disease, namely cirrhosis, is charac...
Autores principales: | Calitz, Carlemi, Rosenquist, Jenny, Degerstedt, Oliver, Khaled, Jaafar, Kopsida, Maria, Fryknäs, Mårten, Lennernäs, Hans, Samanta, Ayan, Heindryckx, Femke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839216/ https://www.ncbi.nlm.nih.gov/pubmed/36639512 http://dx.doi.org/10.1038/s41598-023-27997-3 |
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