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Structural basis for recruitment of host CypA and E3 ubiquitin ligase by maedi-visna virus Vif

Lentiviral Vif molecules target the host antiviral APOBEC3 proteins for destruction in cellular ubiquitin-proteasome pathways. Different lentiviral Vifs have evolved to use the same canonical E3 ubiquitin ligase complexes, along with distinct noncanonical host cofactors for their activities. Unlike...

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Detalles Bibliográficos
Autores principales:	Hu, Yingxia, Gudnadóttir, Ragna B., Knecht, Kirsten M., Arizaga, Fidel, Jónsson, Stefán R., Xiong, Yong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2023
Materias:	Biomedicine and Life Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839330/ https://www.ncbi.nlm.nih.gov/pubmed/36638173 http://dx.doi.org/10.1126/sciadv.add3422

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