Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22

During metastasis, cancer cells invade, intravasate, enter the circulation, extravasate, and colonize target organs. Here, we examined the role of interleukin (IL)-22 in metastasis. Immune cell-derived IL-22 acts on epithelial tissues, promoting regeneration and healing upon tissue damage, but it is...

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Autores principales: Giannou, Anastasios D., Kempski, Jan, Shiri, Ahmad Mustafa, Lücke, Jöran, Zhang, Tao, Zhao, Lilan, Zazara, Dimitra E., Cortesi, Filippo, Riecken, Kristoffer, Amezcua Vesely, Maria Carolina, Low, Jun Siong, Xu, Hao, Kaffe, Eleanna, Garcia-Perez, Laura, Agalioti, Theodora, Yamada, Yoshito, Jungraithmayr, Wolfgang, Zigmond, Ehud, Karstens, Karl-Frederick, Steglich, Babett, Wagner, Jonas, Konczalla, Leonie, Carambia, Antonella, Schulze, Kornelius, von Felden, Johann, May, Peter, Briukhovetska, Daria, Bedke, Tanja, Brockmann, Leonie, Starzonek, Sarah, Lange, Tobias, Koch, Claudia, Riethdorf, Sabine, Pelczar, Penelope, Böttcher, Marius, Sabihi, Morsal, Huber, Francis J., Reeh, Matthias, Grass, Julia Kristin, Wahib, Ramez, Seese, Hannes, Stüben, Björn-Ole, Fard-Aghaie, Mohammad, Duprée, Anna, Scognamiglio, Pasquale, Plitzko, Gabriel, Meiners, Jan, Soukou, Shiwa, Wittek, Agnes, Manthey, Caroline, Maroulis, Ioannis C., Arck, Petra C., Perez, Daniel, Gao, Bin, Zarogiannis, Sotirios G., Strowig, Till, Pasqualini, Renata, Arap, Wadih, Gosálvez, Javier Suárez, Kobold, Sebastian, Prinz, Immo, Guse, Andreas H., Tachezy, Michael, Ghadban, Tarik, Heumann, Asmus, Li, Jun, Melling, Nathaniel, Mann, Oliver, Izbicki, Jakob R., Pantel, Klaus, Schumacher, Udo, Lohse, Ansgar W., Flavell, Richard A., Gagliani, Nicola, Huber, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839362/
https://www.ncbi.nlm.nih.gov/pubmed/36630911
http://dx.doi.org/10.1016/j.immuni.2022.12.014

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