Spurious transcription causing innate immune responses is prevented by 5-hydroxymethylcytosine

Generation of functional transcripts requires transcriptional initiation at regular start sites, avoiding production of aberrant and potentially hazardous aberrant RNAs. The mechanisms maintaining transcriptional fidelity and the impact of spurious transcripts on cellular physiology and organ functi...

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Detalles Bibliográficos
Autores principales: Wu, Fan, Li, Xiang, Looso, Mario, Liu, Hang, Ding, Dong, Günther, Stefan, Kuenne, Carsten, Liu, Shuya, Weissmann, Norbert, Boettger, Thomas, Atzberger, Ann, Kolahian, Saeed, Renz, Harald, Offermanns, Stefan, Gärtner, Ulrich, Potente, Michael, Zhou, Yonggang, Yuan, Xuejun, Braun, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839451/
https://www.ncbi.nlm.nih.gov/pubmed/36539616
http://dx.doi.org/10.1038/s41588-022-01252-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839451/
https://www.ncbi.nlm.nih.gov/pubmed/36539616
http://dx.doi.org/10.1038/s41588-022-01252-3

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