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Control of protein stability by post-translational modifications

Post-translational modifications (PTMs) can occur on specific amino acids localized within regulatory domains of target proteins, which control a protein’s stability. These regions, called degrons, are often controlled by PTMs, which act as signals to expedite protein degradation (PTM-activated degr...

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Detalles Bibliográficos
Autores principales: Lee, Ji Min, Hammarén, Henrik M., Savitski, Mikhail M., Baek, Sung Hee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839724/
https://www.ncbi.nlm.nih.gov/pubmed/36639369
http://dx.doi.org/10.1038/s41467-023-35795-8