CircIFNGR2 enhances proliferation and migration of CRC and induces cetuximab resistance by indirectly targeting KRAS via sponging to MiR-30b

Currently the clinical efficacy of colorectal cancer (CRC) which is the most common malignant tumors over the world has not reached an ideal level. Cetuximab, the monoclonal antibody targeting the extracellular domain of EGFR, has shown its great efficacy in the promotion of apoptosis and the inhibi...

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Detalles Bibliográficos
Autores principales: Zhang, Qi, Zheng, Yifeng, Liu, Jiajia, Tang, Xiaoxiao, Wang, Yuan, Li, Xianzheng, Li, Huibin, Zhou, Xiaoying, Tang, Shiru, Tang, Yitao, Wang, Xiaoyan, He, Han, Li, Tingting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839739/
https://www.ncbi.nlm.nih.gov/pubmed/36639711
http://dx.doi.org/10.1038/s41419-022-05536-8

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