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Mechanical compression creates a quiescent muscle stem cell niche

Tissue stem cell niches are regulated by their mechanical environment, notably the extracellular matrix (ECM). Skeletal muscles consist of bundled myofibers for force transmission. Within this macroscopic architecture, quiescent Pax7-expressing (Pax7(+)) muscle stem cells (MuSCs) are compressed betw...

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Detalles Bibliográficos
Autores principales: Tao, Jiaxiang, Choudhury, Mohammad Ikbal, Maity, Debonil, Kim, Taeki, Sun, Sean X., Fan, Chen-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839757/
https://www.ncbi.nlm.nih.gov/pubmed/36639551
http://dx.doi.org/10.1038/s42003-023-04411-2