Coupled induction of prophage and virulence factors during tick transmission of the Lyme disease spirochete

The alternative sigma factor RpoS plays a central role in the critical host-adaptive response of the Lyme disease spirochete, Borrelia burgdorferi. We previously identified bbd18 as a negative regulator of RpoS but could not inactivate bbd18 in wild-type spirochetes. In the current study we employed...

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Detalles Bibliográficos
Autores principales: Wachter, Jenny, Cheff, Britney, Hillman, Chad, Carracoi, Valentina, Dorward, David W., Martens, Craig, Barbian, Kent, Nardone, Glenn, Renee Olano, L., Kinnersley, Margie, Secor, Patrick R., Rosa, Patricia A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839762/
https://www.ncbi.nlm.nih.gov/pubmed/36639656
http://dx.doi.org/10.1038/s41467-023-35897-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839762/
https://www.ncbi.nlm.nih.gov/pubmed/36639656
http://dx.doi.org/10.1038/s41467-023-35897-3

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