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Evaluation of ABCG2-mediated extra-renal urate excretion in hemodialysis patients

Two-thirds of urate is excreted via the renal pathway and the remaining one-third via the extra-renal pathway, the latter mainly via the intestine in healthy individuals. ABCG2, a urate exporter, is expressed in various tissues including the kidney and intestine, and its dysfunction leads to hyperur...

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Detalles Bibliográficos
Autores principales: Ohashi, Yuki, Toyoda, Masao, Saito, Nobumichi, Koizumi, Masahiro, Kanai, Genta, Komaba, Hirotaka, Kimura, Moritsugu, Wada, Takehiko, Takahashi, Hiroo, Takahashi, Yuichiro, Ishida, Naoto, Kakuta, Takatoshi, Fukagawa, Masafumi, Ichida, Kimiyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839766/
https://www.ncbi.nlm.nih.gov/pubmed/36639673
http://dx.doi.org/10.1038/s41598-022-26519-x