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Evaluation of ABCG2-mediated extra-renal urate excretion in hemodialysis patients
Two-thirds of urate is excreted via the renal pathway and the remaining one-third via the extra-renal pathway, the latter mainly via the intestine in healthy individuals. ABCG2, a urate exporter, is expressed in various tissues including the kidney and intestine, and its dysfunction leads to hyperur...
Autores principales: | Ohashi, Yuki, Toyoda, Masao, Saito, Nobumichi, Koizumi, Masahiro, Kanai, Genta, Komaba, Hirotaka, Kimura, Moritsugu, Wada, Takehiko, Takahashi, Hiroo, Takahashi, Yuichiro, Ishida, Naoto, Kakuta, Takatoshi, Fukagawa, Masafumi, Ichida, Kimiyoshi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839766/ https://www.ncbi.nlm.nih.gov/pubmed/36639673 http://dx.doi.org/10.1038/s41598-022-26519-x |
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