Inhibition of CEMIP potentiates the effect of sorafenib on metastatic hepatocellular carcinoma by reducing the stiffness of lung metastases

Hepatocellular carcinoma (HCC) with lung metastasis is associated with poor prognosis and poor therapeutic outcomes. Studies have demonstrated that stiffened stroma can promote metastasis in various tumors. However, how the lung mechanical microenvironment favors circulating tumor cells remains uncl...

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Detalles Bibliográficos
Autores principales: Liu, Mingyu, Xie, Lulu, Zhang, Yuying, Chen, Jianning, Zhang, Xiang, Chen, Ye, Huang, Wensou, Cai, Mingyue, Liang, Licong, Lai, Miaoling, Huang, Jingjun, Guo, Yongjian, Lin, Liteng, Zhu, Kangshun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839779/
https://www.ncbi.nlm.nih.gov/pubmed/36639658
http://dx.doi.org/10.1038/s41419-023-05550-4

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