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The interferon stimulated gene-encoded protein HELZ2 inhibits human LINE-1 retrotransposition and LINE-1 RNA-mediated type I interferon induction

Some interferon stimulated genes (ISGs) encode proteins that inhibit LINE-1 (L1) retrotransposition. Here, we use immunoprecipitation followed by liquid chromatography-tandem mass spectrometry to identify proteins that associate with the L1 ORF1-encoded protein (ORF1p) in ribonucleoprotein particles...

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Detalles Bibliográficos
Autores principales:	Luqman-Fatah, Ahmad, Watanabe, Yuzo, Uno, Kazuko, Ishikawa, Fuyuki, Moran, John V., Miyoshi, Tomoichiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839780/ https://www.ncbi.nlm.nih.gov/pubmed/36639706 http://dx.doi.org/10.1038/s41467-022-35757-6

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