Interleukin-13 and its receptor are synaptic proteins involved in plasticity and neuroprotection

Immune system molecules are expressed by neurons, yet their functions are often unknown. We have identified IL-13 and its receptor IL-13Ra1 as neuronal, synaptic proteins in mouse, rat, and human brains, whose engagement upregulates the phosphorylation of NMDAR and AMPAR subunits and, in turn, incre...

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Detalles Bibliográficos
Autores principales: Li, Shun, olde Heuvel, Florian, Rehman, Rida, Aousji, Oumayma, Froehlich, Albrecht, Li, Zhenghui, Jark, Rebecca, Zhang, Wanhong, Conquest, Alison, Woelfle, Sarah, Schoen, Michael, O´Meara, Caitlin C., Reinhardt, Richard Lee, Voehringer, David, Kassubek, Jan, Ludolph, Albert, Huber-Lang, Markus, Knöll, Bernd, Morganti-Kossmann, Maria Cristina, Brockmann, Marisa M., Boeckers, Tobias, Roselli, Francesco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839781/
https://www.ncbi.nlm.nih.gov/pubmed/36639371
http://dx.doi.org/10.1038/s41467-023-35806-8

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