Tumor Cell‐Intrinsic SETD2 Deficiency Reprograms Neutrophils to Foster Immune Escape in Pancreatic Tumorigenesis

Genetic and epigenetic alterations play central roles in shaping the immunosuppressive tumor microenvironment (TME) to evade immune surveillance. The previous study shows that SETD2‐H3K36me3 loss promotes KRAS‐induced pancreatic tumorigenesis. However, little is known about its role in remodeling th...

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Detalles Bibliográficos
Autores principales: Niu, Ningning, Shen, Xuqing, Zhang, Li, Chen, Yueyue, Lu, Ping, Yang, Wenjuan, Liu, Mingzhu, Shi, Juanjuan, Xu, Dapeng, Tang, Yingying, Yang, Xiaotong, Weng, Yawen, Zhao, Xinxin, Wu, Lian‐Ming, Sun, Yongwei, Xue, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839845/
https://www.ncbi.nlm.nih.gov/pubmed/36453584
http://dx.doi.org/10.1002/advs.202202937

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839845/
https://www.ncbi.nlm.nih.gov/pubmed/36453584
http://dx.doi.org/10.1002/advs.202202937

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