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Tumor Cell‐Intrinsic SETD2 Deficiency Reprograms Neutrophils to Foster Immune Escape in Pancreatic Tumorigenesis
Genetic and epigenetic alterations play central roles in shaping the immunosuppressive tumor microenvironment (TME) to evade immune surveillance. The previous study shows that SETD2‐H3K36me3 loss promotes KRAS‐induced pancreatic tumorigenesis. However, little is known about its role in remodeling th...
Autores principales: | Niu, Ningning, Shen, Xuqing, Zhang, Li, Chen, Yueyue, Lu, Ping, Yang, Wenjuan, Liu, Mingzhu, Shi, Juanjuan, Xu, Dapeng, Tang, Yingying, Yang, Xiaotong, Weng, Yawen, Zhao, Xinxin, Wu, Lian‐Ming, Sun, Yongwei, Xue, Jing |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839845/ https://www.ncbi.nlm.nih.gov/pubmed/36453584 http://dx.doi.org/10.1002/advs.202202937 |
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