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High‐Quality Artery Monitoring and Pathology Imaging Achieved by High‐Performance Synchronous Electrical and Optical Output of Near‐Infrared Organic Photodetector

Near‐infrared organic photodetectors (NIR‐OPDs) are significant technologies in emerging biomedicine applications for uniquely wearable, noninvasive, low‐cost advantages. However, biosignals are weak and changing rapidly so practical biodetection and bioimaging are still challenging for NIR‐OPDs. He...

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Autores principales: He, Zeyu, Du, Xiaoyang, Zheng, Caijun, Yu, Xin, Lin, Hui, Tao, Silu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839857/
https://www.ncbi.nlm.nih.gov/pubmed/36403247
http://dx.doi.org/10.1002/advs.202203870
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author He, Zeyu
Du, Xiaoyang
Zheng, Caijun
Yu, Xin
Lin, Hui
Tao, Silu
author_facet He, Zeyu
Du, Xiaoyang
Zheng, Caijun
Yu, Xin
Lin, Hui
Tao, Silu
author_sort He, Zeyu
collection PubMed
description Near‐infrared organic photodetectors (NIR‐OPDs) are significant technologies in emerging biomedicine applications for uniquely wearable, noninvasive, low‐cost advantages. However, biosignals are weak and changing rapidly so practical biodetection and bioimaging are still challenging for NIR‐OPDs. Herein, high‐performance NIR‐OPDs with synchronous optical output are realized by recombining anode‐injected electrons with photogenerated holes on emitters. Owing to high detection performance of 4.5 × 10(12) Jones detectivity and 120 kHz −3 dB bandwidth, five arteries are monitored by transmission‐type method and cardiac cycle is analyzed. Importantly, the synchronous optical output is direct emission demonstrating outstanding photon conversion efficiency approaching 20% and luminance signal‐to‐noise ratio over 8000. Consequently, pathology imaging is directly developed without complex readout circuits and arrays from which squamous metaplasia of cervix and carcinoma of large intestine are observed clearly. The NIR‐OPD demonstrates strategies for high‐performance synchronous electrical/optical output and directly imaging. Biomedicine applications implemented here are high level, representing important steps for NIR‐OPDs toward providing clues for clinical diagnosis.
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spelling pubmed-98398572023-01-18 High‐Quality Artery Monitoring and Pathology Imaging Achieved by High‐Performance Synchronous Electrical and Optical Output of Near‐Infrared Organic Photodetector He, Zeyu Du, Xiaoyang Zheng, Caijun Yu, Xin Lin, Hui Tao, Silu Adv Sci (Weinh) Research Articles Near‐infrared organic photodetectors (NIR‐OPDs) are significant technologies in emerging biomedicine applications for uniquely wearable, noninvasive, low‐cost advantages. However, biosignals are weak and changing rapidly so practical biodetection and bioimaging are still challenging for NIR‐OPDs. Herein, high‐performance NIR‐OPDs with synchronous optical output are realized by recombining anode‐injected electrons with photogenerated holes on emitters. Owing to high detection performance of 4.5 × 10(12) Jones detectivity and 120 kHz −3 dB bandwidth, five arteries are monitored by transmission‐type method and cardiac cycle is analyzed. Importantly, the synchronous optical output is direct emission demonstrating outstanding photon conversion efficiency approaching 20% and luminance signal‐to‐noise ratio over 8000. Consequently, pathology imaging is directly developed without complex readout circuits and arrays from which squamous metaplasia of cervix and carcinoma of large intestine are observed clearly. The NIR‐OPD demonstrates strategies for high‐performance synchronous electrical/optical output and directly imaging. Biomedicine applications implemented here are high level, representing important steps for NIR‐OPDs toward providing clues for clinical diagnosis. John Wiley and Sons Inc. 2022-11-20 /pmc/articles/PMC9839857/ /pubmed/36403247 http://dx.doi.org/10.1002/advs.202203870 Text en © 2022 The Authors. Advanced Science published by Wiley‐VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
He, Zeyu
Du, Xiaoyang
Zheng, Caijun
Yu, Xin
Lin, Hui
Tao, Silu
High‐Quality Artery Monitoring and Pathology Imaging Achieved by High‐Performance Synchronous Electrical and Optical Output of Near‐Infrared Organic Photodetector
title High‐Quality Artery Monitoring and Pathology Imaging Achieved by High‐Performance Synchronous Electrical and Optical Output of Near‐Infrared Organic Photodetector
title_full High‐Quality Artery Monitoring and Pathology Imaging Achieved by High‐Performance Synchronous Electrical and Optical Output of Near‐Infrared Organic Photodetector
title_fullStr High‐Quality Artery Monitoring and Pathology Imaging Achieved by High‐Performance Synchronous Electrical and Optical Output of Near‐Infrared Organic Photodetector
title_full_unstemmed High‐Quality Artery Monitoring and Pathology Imaging Achieved by High‐Performance Synchronous Electrical and Optical Output of Near‐Infrared Organic Photodetector
title_short High‐Quality Artery Monitoring and Pathology Imaging Achieved by High‐Performance Synchronous Electrical and Optical Output of Near‐Infrared Organic Photodetector
title_sort high‐quality artery monitoring and pathology imaging achieved by high‐performance synchronous electrical and optical output of near‐infrared organic photodetector
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839857/
https://www.ncbi.nlm.nih.gov/pubmed/36403247
http://dx.doi.org/10.1002/advs.202203870
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