Cargando…

Silencing of IRF8 Mediated by m6A Modification Promotes the Progression of T‐Cell Acute Lymphoblastic Leukemia

T‐cell acute lymphoblastic leukemia (T‐ALL) is an aggressive hematological malignancy with a poor prognosis, urging for novel therapeutic targets and treatment strategies. N6‐methyladenosine (m6A) is a crucial methylation modification that affects the pathogenesis of leukemia by regulating the mRNA...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhou, Ying, Ji, Min, Xia, Yuan, Han, Xiaoyu, Li, Mingying, Li, Wei, Sun, Tao, Zhang, Jingru, Lu, Fei, Sun, Yanping, Liu, Na, Li, Jingxin, Ma, Daoxin, Ye, Jingjing, Ji, Chunyan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9839875/ https://www.ncbi.nlm.nih.gov/pubmed/36478193 http://dx.doi.org/10.1002/advs.202201724

Ejemplares similares

Notch1 is required for hypoxia-induced proliferation, invasion and chemoresistance of T-cell acute lymphoblastic leukemia cells
por: Zou, Jie, et al.
Publicado: (2013)

Inhibition of the m(6)A reader IGF2BP2 as a strategy against T-cell acute lymphoblastic leukemia
por: Feng, Panpan, et al.
Publicado: (2022)

NCBP1 enhanced proliferation of DLBCL cells via METTL3-mediated m6A modification of c-Myc
por: Meng, Sibo, et al.
Publicado: (2023)

DEX‐Induced SREBF1 Promotes BMSCs Differentiation into Adipocytes to Attract and Protect Residual T‐Cell Acute Lymphoblastic Leukemia Cells After Chemotherapy
por: Jia, Ruinan, et al.
Publicado: (2023)

Subclones of bone marrow CD34(+) cells in acute myeloid leukemia at diagnosis confer responses of patients to induction chemotherapy
por: Jia, Ruinan, et al.
Publicado: (2022)

The prognostic marker FLVCR2 associated with tumor progression and immune infiltration for acute myeloid leukemia
por: Su, Xiuhua, et al.
Publicado: (2022)

TNFAIP8 promotes AML chemoresistance by activating ERK signaling pathway through interaction with Rac1
por: Pang, Yihua, et al.
Publicado: (2020)

Novel AF1q/MLLT11 favorably affects imatinib resistance and cell survival in chronic myeloid leukemia
por: Li, Wei, et al.
Publicado: (2018)

DEX‐Induced SREBF1 Promotes BMSCs Differentiation into Adipocytes to Attract and Protect Residual T‐Cell Acute Lymphoblastic Leukemia Cells After Chemotherapy (Adv. Sci. 19/2023)
por: Jia, Ruinan, et al.
Publicado: (2023)

METTL3 mediates chemoresistance by enhancing AML homing and engraftment via ITGA4
por: Li, Mingying, et al.
Publicado: (2022)

Restoration of miR-23a expression by chidamide sensitizes CML cells to imatinib treatment with concomitant downregulation of CRYAB
por: Zhu, Xunxun, et al.
Publicado: (2022)

SMG1 Acts as a Novel Potential Tumor Suppressor with Epigenetic Inactivation in Acute Myeloid Leukemia
por: Du, Yahui, et al.
Publicado: (2014)

Immune checkpoint‐related gene polymorphisms are associated with acute myeloid leukemia
por: Wu, Yuyan, et al.
Publicado: (2023)

Investigation of NF-κB-94ins/del ATTG and CARD8 (rs2043211) Gene Polymorphism in Acute Lymphoblastic Leukemia
por: Zhang, Chen, et al.
Publicado: (2019)

DNA damage to bone marrow stromal cells by antileukemia drugs induces chemoresistance in acute myeloid leukemia via paracrine FGF10–FGFR2 signaling
por: Yu, Shuang, et al.
Publicado: (2022)

PAK1 Mediates Bone Marrow Stromal Cell-Induced Drug Resistance in Acute Myeloid Leukemia via ERK1/2 Signaling Pathway
por: Li, Banban, et al.
Publicado: (2021)

Aberrant expression of CD133 and CD82 in patients with pediatric acute lymphoblastic leukemia and the clinical significance
por: Ji, Hongyan, et al.
Publicado: (2017)

Transcription factor IRF8 directs a silencing programme for T(H)17 cell differentiation
por: Ouyang, Xinshou, et al.
Publicado: (2011)

Myeloid-Derived Suppressor Cells and γδT17 Cells Contribute to the Development of Gastric MALT Lymphoma in H. felis-Infected Mice
por: Zhao, Yanan, et al.
Publicado: (2020)

The emerging roles of Notch signaling in leukemia and stem cells
por: Liu, Na, et al.
Publicado: (2013)

Role of CDH23 as a prognostic biomarker and its relationship with immune infiltration in acute myeloid leukemia
por: Yang, Jiao, et al.
Publicado: (2022)

The Mutation Profile of Calreticulin in Patients with Myeloproliferative Neoplasms and Acute Leukemia
por: Wang, Jingyi, et al.
Publicado: (2016)

Mitochondrial apoptosis-related gene polymorphisms are associated with responses to anthracycline-based chemotherapy in acute myeloid leukaemia
por: Meng, Guangqiang, et al.
Publicado: (2023)

Acute B Lymphoblastic Leukemia Developing in Patients with Multiple Myeloma: Presentation of Two Cases
por: Mei, Jiang, et al.
Publicado: (2019)

Epigenetic Silencing of IRF7 and/or IRF5 in Lung Cancer Cells Leads to Increased Sensitivity to Oncolytic Viruses
por: Li, Qunfang, et al.
Publicado: (2011)

Aberrant methylation and silencing of IRF8 expression in non-small cell lung cancer
por: SUZUKI, MAKOTO, et al.
Publicado: (2014)

Epigenetic Modifications in Pediatric Acute Lymphoblastic Leukemia
por: Burke, Michael J., et al.
Publicado: (2014)

The Alteration and Clinical Significance of Th22/Th17/Th1 Cells in Patients with Chronic Myeloid Leukemia
por: Chen, Ping, et al.
Publicado: (2015)

Homodimer-mediated phosphorylation of C/EBPα-p42 S16 modulates acute myeloid leukaemia differentiation through liquid-liquid phase separation
por: Wang, Dongmei, et al.
Publicado: (2023)

Deacetylation of YAP1 Promotes the Resistance to Chemo- and Targeted Therapy in FLT3-ITD(+) AML Cells
por: Feng, Panpan, et al.
Publicado: (2022)

Tagging Single Nucleotide Polymorphisms in the IRF1 and IRF8 Genes and Tuberculosis Susceptibility
por: Ding, Shiping, et al.
Publicado: (2012)

Grass Carp (Ctenopharyngodon idella) KAT8 Inhibits IFN 1 Response Through Acetylating IRF3/IRF7
por: Li, Meifeng, et al.
Publicado: (2022)

Gene expression profiling of the DNMT3A R882 mutation in acute leukemia
por: HUANG, XIANGNAN, et al.
Publicado: (2013)

The Prognostic Significance of IRF8 Transcripts in Adult Patients with Acute Myeloid Leukemia
por: Pogosova-Agadjanyan, Era L., et al.
Publicado: (2013)

Neuropathy correlated with imbalanced Foxp3/IL-17 in bone marrow microenvironment of patients with acute myeloid leukemia
por: Chen, Chen, et al.
Publicado: (2016)

Lkb1 aggravates diffuse large B-cell lymphoma by promoting the function of Treg cells and immune escape
por: Su, Xiuhua, et al.
Publicado: (2022)

Ubiquitination modification: critical regulation of IRF family stability and activity
por: Liu, Bao-qin, et al.
Publicado: (2020)

Novel gene signature reveals prognostic model in acute lymphoblastic leukemia
por: Chen, Panpan, et al.
Publicado: (2022)

YBX1 as an oncogenic factor in T-cell acute lymphoblastic leukemia
por: Li, Huan, et al.
Publicado: (2023)

Epigenetic silencing of UBXN8 contributes to leukemogenesis in t(8;21) acute myeloid leukemia
por: Yang, Erna, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_qlncn0qnpu4h8q9raf0bo3qcq2