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An Unusual Case of Myopericarditis in a Young Woman

A 48-year-old woman with no history of cardiovascular risk factors was admitted to the emergency room with complaints of angor, dyspnea, and fever in the last 24 h. She was referred for xerostomia and xerophthalmia since 2015. At examination, the patient was polypneic with bibasal crackles. Blood te...

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Autores principales: Figueiredo, Inês, Kozyar, Inna, Duarte, Cristina, Guimarães, Francisco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840093/
https://www.ncbi.nlm.nih.gov/pubmed/36654539
http://dx.doi.org/10.7759/cureus.32542
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author Figueiredo, Inês
Kozyar, Inna
Duarte, Cristina
Guimarães, Francisco
author_facet Figueiredo, Inês
Kozyar, Inna
Duarte, Cristina
Guimarães, Francisco
author_sort Figueiredo, Inês
collection PubMed
description A 48-year-old woman with no history of cardiovascular risk factors was admitted to the emergency room with complaints of angor, dyspnea, and fever in the last 24 h. She was referred for xerostomia and xerophthalmia since 2015. At examination, the patient was polypneic with bibasal crackles. Blood tests showed leukocytosis and increased high sensitivity troponin I and C-reactive protein (CRP). The echocardiogram revealed a small pericardial effusion.  She was diagnosed with myopericarditis and started acetylsalicylic acid (ASA) and colchicine. Laboratory tests indicated the presence of positive antinuclear antibodies, double-strain DNA antibodies (anti-dsDNA), anti-Sjögren's-syndrome-related antigen A (anti-SSA), and lupus anticoagulant antibodies. Positivity for phase II immunoglobulin M and G for Coxiella burnetti was detected. As it fulfills the diagnostic criteria for a possible flare of systemic lupus erythematosus (SLE) and SS (triggered by a possible infection by C. burnetti) the patient started immunosuppressive therapy. A complete resolution of symptoms with normalization of CRP and troponin I values were observed.
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spelling pubmed-98400932023-01-17 An Unusual Case of Myopericarditis in a Young Woman Figueiredo, Inês Kozyar, Inna Duarte, Cristina Guimarães, Francisco Cureus Internal Medicine A 48-year-old woman with no history of cardiovascular risk factors was admitted to the emergency room with complaints of angor, dyspnea, and fever in the last 24 h. She was referred for xerostomia and xerophthalmia since 2015. At examination, the patient was polypneic with bibasal crackles. Blood tests showed leukocytosis and increased high sensitivity troponin I and C-reactive protein (CRP). The echocardiogram revealed a small pericardial effusion.  She was diagnosed with myopericarditis and started acetylsalicylic acid (ASA) and colchicine. Laboratory tests indicated the presence of positive antinuclear antibodies, double-strain DNA antibodies (anti-dsDNA), anti-Sjögren's-syndrome-related antigen A (anti-SSA), and lupus anticoagulant antibodies. Positivity for phase II immunoglobulin M and G for Coxiella burnetti was detected. As it fulfills the diagnostic criteria for a possible flare of systemic lupus erythematosus (SLE) and SS (triggered by a possible infection by C. burnetti) the patient started immunosuppressive therapy. A complete resolution of symptoms with normalization of CRP and troponin I values were observed. Cureus 2022-12-15 /pmc/articles/PMC9840093/ /pubmed/36654539 http://dx.doi.org/10.7759/cureus.32542 Text en Copyright © 2022, Figueiredo et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Figueiredo, Inês
Kozyar, Inna
Duarte, Cristina
Guimarães, Francisco
An Unusual Case of Myopericarditis in a Young Woman
title An Unusual Case of Myopericarditis in a Young Woman
title_full An Unusual Case of Myopericarditis in a Young Woman
title_fullStr An Unusual Case of Myopericarditis in a Young Woman
title_full_unstemmed An Unusual Case of Myopericarditis in a Young Woman
title_short An Unusual Case of Myopericarditis in a Young Woman
title_sort unusual case of myopericarditis in a young woman
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840093/
https://www.ncbi.nlm.nih.gov/pubmed/36654539
http://dx.doi.org/10.7759/cureus.32542
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