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Isotropic conductive paste for bioresorbable electronics

Bioresorbable implantable medical devices can be employed in versatile clinical scenarios that burden patients with complications and surgical removal of conventional devices. However, a shortage of suitable electricalinterconnection materials limits the development of bioresorbable electronic syste...

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Detalles Bibliográficos
Autores principales: Kim, Kyung Su, Maeng, Woo-Youl, Kim, Seongchan, Lee, Gyubok, Hong, Minki, Kim, Ga-been, Kim, Jaewon, Kim, Sungeun, Han, Seunghun, Yoo, Jaeyoung, Lee, Hyojin, Lee, Kangwon, Koo, Jahyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840151/
https://www.ncbi.nlm.nih.gov/pubmed/36647537
http://dx.doi.org/10.1016/j.mtbio.2023.100541
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author Kim, Kyung Su
Maeng, Woo-Youl
Kim, Seongchan
Lee, Gyubok
Hong, Minki
Kim, Ga-been
Kim, Jaewon
Kim, Sungeun
Han, Seunghun
Yoo, Jaeyoung
Lee, Hyojin
Lee, Kangwon
Koo, Jahyun
author_facet Kim, Kyung Su
Maeng, Woo-Youl
Kim, Seongchan
Lee, Gyubok
Hong, Minki
Kim, Ga-been
Kim, Jaewon
Kim, Sungeun
Han, Seunghun
Yoo, Jaeyoung
Lee, Hyojin
Lee, Kangwon
Koo, Jahyun
author_sort Kim, Kyung Su
collection PubMed
description Bioresorbable implantable medical devices can be employed in versatile clinical scenarios that burden patients with complications and surgical removal of conventional devices. However, a shortage of suitable electricalinterconnection materials limits the development of bioresorbable electronic systems. Therefore, this study highlights a highly conductive, naturally resorbable paste exhibiting enhanced electrical conductivity and mechanical stability that can solve the existing problems of bioresorbable interconnections. Multifaceted experiments on electrical and physical properties were used to optimize the composition of pastes containing beeswax, submicron tungstenparticles, and glycofurol. These pastes embody isotropic conductive paths for three-dimensional interconnects and function as antennas, sensors, and contact pads for bioresorbable electronic devices. The degradation behavior in aqueous solutions was used to assess its stability and ability to retain electrical conductance (∼7 ​kS/m) and structural form over the requisite dissolution period. In vitro and in vivo biocompatibility tests clarified the safety of the paste as an implantable material.
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spelling pubmed-98401512023-01-15 Isotropic conductive paste for bioresorbable electronics Kim, Kyung Su Maeng, Woo-Youl Kim, Seongchan Lee, Gyubok Hong, Minki Kim, Ga-been Kim, Jaewon Kim, Sungeun Han, Seunghun Yoo, Jaeyoung Lee, Hyojin Lee, Kangwon Koo, Jahyun Mater Today Bio Full Length Article Bioresorbable implantable medical devices can be employed in versatile clinical scenarios that burden patients with complications and surgical removal of conventional devices. However, a shortage of suitable electricalinterconnection materials limits the development of bioresorbable electronic systems. Therefore, this study highlights a highly conductive, naturally resorbable paste exhibiting enhanced electrical conductivity and mechanical stability that can solve the existing problems of bioresorbable interconnections. Multifaceted experiments on electrical and physical properties were used to optimize the composition of pastes containing beeswax, submicron tungstenparticles, and glycofurol. These pastes embody isotropic conductive paths for three-dimensional interconnects and function as antennas, sensors, and contact pads for bioresorbable electronic devices. The degradation behavior in aqueous solutions was used to assess its stability and ability to retain electrical conductance (∼7 ​kS/m) and structural form over the requisite dissolution period. In vitro and in vivo biocompatibility tests clarified the safety of the paste as an implantable material. Elsevier 2023-01-04 /pmc/articles/PMC9840151/ /pubmed/36647537 http://dx.doi.org/10.1016/j.mtbio.2023.100541 Text en © 2023 The Authors https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Full Length Article
Kim, Kyung Su
Maeng, Woo-Youl
Kim, Seongchan
Lee, Gyubok
Hong, Minki
Kim, Ga-been
Kim, Jaewon
Kim, Sungeun
Han, Seunghun
Yoo, Jaeyoung
Lee, Hyojin
Lee, Kangwon
Koo, Jahyun
Isotropic conductive paste for bioresorbable electronics
title Isotropic conductive paste for bioresorbable electronics
title_full Isotropic conductive paste for bioresorbable electronics
title_fullStr Isotropic conductive paste for bioresorbable electronics
title_full_unstemmed Isotropic conductive paste for bioresorbable electronics
title_short Isotropic conductive paste for bioresorbable electronics
title_sort isotropic conductive paste for bioresorbable electronics
topic Full Length Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840151/
https://www.ncbi.nlm.nih.gov/pubmed/36647537
http://dx.doi.org/10.1016/j.mtbio.2023.100541
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