Nesprin-1 LINC complexes recruit microtubule cytoskeleton proteins and drive pathology in Lmna-mutant striated muscle

Mutations in LMNA, the gene encoding A-type lamins, cause laminopathies—diseases of striated muscle and other tissues. The aetiology of laminopathies has been attributed to perturbation of chromatin organization or structural weakening of the nuclear envelope (NE) such that the nucleus becomes more...

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Detalles Bibliográficos
Autores principales: Leong, Ei Leen, Khaing, Nyein Thet, Cadot, Bruno, Hong, Wei Liang, Kozlov, Serguei, Werner, Hendrikje, Wong, Esther Sook Miin, Stewart, Colin L, Burke, Brian, Lee, Yin Loon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840208/
https://www.ncbi.nlm.nih.gov/pubmed/35925868
http://dx.doi.org/10.1093/hmg/ddac179

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