Cargando…

Long-term impact of paediatric critical illness on the difference between epigenetic and chronological age in relation to physical growth

BACKGROUND: Altered DNA-methylation affects biological ageing in adults and developmental processes in children. DNA-methylation is altered by environmental factors, trauma and illnesses. We hypothesised that paediatric critical illness, and the nutritional management in the paediatric intensive car...

Descripción completa

Detalles Bibliográficos
Autores principales:	Verlinden, Ines, Coppens, Grégoire, Vanhorebeek, Ilse, Güiza, Fabian, Derese, Inge, Wouters, Pieter J., Joosten, Koen F., Verbruggen, Sascha C., Van den Berghe, Greet
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840263/ https://www.ncbi.nlm.nih.gov/pubmed/36639798 http://dx.doi.org/10.1186/s13148-023-01424-w

Ejemplares similares

Assessment of aberrant DNA methylation two years after paediatric critical illness: a pre-planned secondary analysis of the international PEPaNIC trial
por: Coppens, Grégoire, et al.
Publicado: (2022)

Time course of altered DNA methylation evoked by critical illness and by early administration of parenteral nutrition in the paediatric ICU
por: Verlinden, Ines, et al.
Publicado: (2020)

Abnormal DNA methylation within genes of the steroidogenesis pathway two years after paediatric critical illness and association with stunted growth in height further in time
por: Vanhorebeek, Ilse, et al.
Publicado: (2023)

THU155 Aberrant DNA Methylation Within Genes Of The HPA-axis Two Years After Paediatric Critical Illness, Role Of Glucocorticoid Treatment And Association With Impaired Physical And Neurocognitive Development.
por: Coppens, Gregoire, et al.
Publicado: (2023)

OR17-1 Changes in the Hypothalamic-Pituitary-Adrenal Axis during Pediatric Critical Illness
por: Jacobs, An, et al.
Publicado: (2019)

Health-related quality of life of children and their parents 2 years after critical illness: pre-planned follow-up of the PEPaNIC international, randomized, controlled trial
por: Hordijk, José, et al.
Publicado: (2020)

Phasing out DEHP from plastic indwelling medical devices used for intensive care: Does it reduce the long-term attention deficit of critically ill children?
por: Vanhorebeek, Ilse, et al.
Publicado: (2022)

Role of age of critically ill children at time of exposure to early or late parenteral nutrition in determining the impact hereof on long-term neurocognitive development: A secondary analysis of the PEPaNIC-RCT
por: Verlinden, Ines, et al.
Publicado: (2021)

SUN-072 Age of Critically Ill Children at Time of Exposure to Early Parenteral Nutrition Determines Its Impact on Long-Term Physical and Cognitive Development
por: Verlinden, Ines, et al.
Publicado: (2020)

Differential DNA methylation by early versus late parenteral nutrition in the PICU: a biological basis for its impact on emotional and behavioral problems documented 4 years later
por: Jacobs, An, et al.
Publicado: (2021)

Physical, Emotional/Behavioral, and Neurocognitive Developmental Outcomes From 2 to 4 Years After PICU Admission: A Secondary Analysis of the Early Versus Late Parenteral Nutrition Randomized Controlled Trial Cohort*
por: Verlinden, Ines, et al.
Publicado: (2022)

The association of hypoglycemia with outcome of critically ill children in relation to nutritional and blood glucose control strategies
por: Gunst, Jan, et al.
Publicado: (2023)

Leukocyte telomere length in paediatric critical illness: effect of early parenteral nutrition
por: Verstraete, Sören, et al.
Publicado: (2018)

Dynamics and prognostic value of the hypothalamus–pituitary–adrenal axis responses to pediatric critical illness and association with corticosteroid treatment: a prospective observational study
por: Jacobs, An, et al.
Publicado: (2019)

MON-LB012 Long-Term Developmental Impact of Withholding Parenteral Nutrition in Pediatric-ICU: A 4-Year Follow-Up of the Pepanic Randomized Controlled Trial
por: Jacobs, An, et al.
Publicado: (2020)

Impact of critical illness and withholding of early parenteral nutrition in the pediatric intensive care unit on long-term physical performance of children: a 4-year follow-up of the PEPaNIC randomized controlled trial
por: Vanhorebeek, Ilse, et al.
Publicado: (2022)

DNA methylation alterations in muscle of critically ill patients
por: Van Dyck, Lisa, et al.
Publicado: (2022)

Persisting neuroendocrine abnormalities and their association with physical impairment 5 years after critical illness
por: Vanhorebeek, Ilse, et al.
Publicado: (2021)

SAT-724 Endocrine Disruption by Phthalate Exposure in the Pediatric Intensive Care Unit
por: Jacobs, An, et al.
Publicado: (2020)

Health-related quality of life of children and their parents 6 months after children’s critical illness
por: Hordijk, José, et al.
Publicado: (2019)

Early Supplemental Parenteral Nutrition in Critically Ill Children: An Update
por: Jacobs, An, et al.
Publicado: (2019)

Prevalence and Prognostic Value of Abnormal Liver Test Results in Critically Ill Children and the Impact of Delaying Parenteral Nutrition*
por: Jenniskens, Marc, et al.
Publicado: (2018)

Impact of withholding early parenteral nutrition completing enteral nutrition in pediatric critically ill patients (PEPaNIC trial): study protocol for a randomized controlled trial
por: Fivez, Tom, et al.
Publicado: (2015)

OR16-4 The Growth Hormone Axis in Relation to Muscle Weakness in the ICU: Effect of Early Macronutrient Deficit
por: Van Dyck, Lisa, et al.
Publicado: (2019)

The epigenetic legacy of ICU feeding and its consequences
por: Vanhorebeek, Ilse, et al.
Publicado: (2023)

Cost-effectiveness study of early versus late parenteral nutrition in critically ill children (PEPaNIC): preplanned secondary analysis of a multicentre randomised controlled trial
por: van Puffelen, Esther, et al.
Publicado: (2018)

The clinical potential of GDF15 as a “ready-to-feed indicator” for critically ill adults
por: Van Dyck, Lisa, et al.
Publicado: (2020)

Towards a fasting-mimicking diet for critically ill patients: the pilot randomized crossover ICU-FM-1 study
por: Van Dyck, Lisa, et al.
Publicado: (2020)

The soluble mannose receptor (sMR/sCD206) in critically ill patients with invasive fungal infections, bacterial infections or non-infectious inflammation: a secondary analysis of the EPaNIC RCT
por: De Vlieger, Greet, et al.
Publicado: (2019)

SAT-155 Temporal Activation of the Unfolded Protein Response and Concomitant Downregulation of Key Hepatic Transcription Factors in Critical Illness
por: Vankrunkelsven, Wouter, et al.
Publicado: (2019)

Outcomes of Delaying Parenteral Nutrition for 1 Week vs Initiation Within 24 Hours Among Undernourished Children in Pediatric Intensive Care: A Subanalysis of the PEPaNIC Randomized Clinical Trial
por: van Puffelen, Esther, et al.
Publicado: (2018)

OR26-4 Glucocorticoid Receptor Expression and Signaling During Critical Illness, in Relation to the Duration of Illness and the Systemic Glucocorticoid Availability: A Prospective, Observational, Cross-Sectional Human and a Translational Mouse Study
por: Téblick, Arno, et al.
Publicado: (2022)

Skeletal Muscle Myokine Expression in Critical Illness, Association With Outcome and Impact of Therapeutic Interventions
por: Vanhorebeek, Ilse, et al.
Publicado: (2023)

Postoperative Cerebral Oxygen Saturation in Children After Congenital Cardiac Surgery and Long-Term Total Intelligence Quotient: A Prospective Observational Study
por: Carra, Giorgia, et al.
Publicado: (2021)

Impact of duration of critical illness and level of systemic glucocorticoid availability on tissue-specific glucocorticoid receptor expression and actions: A prospective, observational, cross-sectional human and two translational mouse studies
por: Téblick, Arno, et al.
Publicado: (2022)

Neurocognition after paediatric heart surgery: a systematic review and meta-analysis
por: Sterken, Caroline, et al.
Publicado: (2015)

International survey of De-implementation of initiating parenteral nutrition early in Paediatric intensive care units
por: van Puffelen, Esther, et al.
Publicado: (2019)

Impact of early versus late parenteral nutrition on morphological and molecular markers of atrophy and autophagy in skeletal muscle of critically ill patients
por: Vanhorebeek, I, et al.
Publicado: (2013)

The Role of Autophagy in Critical Illness-induced Liver Damage
por: Thiessen, Steven E., et al.
Publicado: (2017)

Receptor for advanced glycation end products axis in critically ill patients
por: Ingels, C, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_bv232pa7c2iqne64j4lbbf5bau