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Bilateral synchronous testicular cancer: A case report
INTRODUCTION AND IMPORTANCE: Testicular cancer is the most common type of malignancy in young adult males, accounting for 1 % of all cancer diagnosis in men and 5 % of all urologic tumors. It is one of the malignancies with the highest cure rate. Bilateral germ cell tumor of the testicles is rare, r...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840355/ https://www.ncbi.nlm.nih.gov/pubmed/36640464 http://dx.doi.org/10.1016/j.ijscr.2022.107870 |
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author | Ginting, Jeremy Thompson Sihombing, Bungaran Warli, Syah Mirsya Siregar, Ginanda Putra Prapiska, Fauriski Febrian |
author_facet | Ginting, Jeremy Thompson Sihombing, Bungaran Warli, Syah Mirsya Siregar, Ginanda Putra Prapiska, Fauriski Febrian |
author_sort | Ginting, Jeremy Thompson |
collection | PubMed |
description | INTRODUCTION AND IMPORTANCE: Testicular cancer is the most common type of malignancy in young adult males, accounting for 1 % of all cancer diagnosis in men and 5 % of all urologic tumors. It is one of the malignancies with the highest cure rate. Bilateral germ cell tumor of the testicles is rare, representing only 1 % of all new cases of testicular cancer, around 30 % of which occur synchronously. Interestingly, there is not yet an occurrence where the bilateral synchronous testicular cancer has different histopathological type. CASE PRESENTATION: In this paper, we performed bilateral radical orchiectomy in different occasion, followed by adjuvant chemotherapy (BEP regiment). CLINICAL DISCUSSION: Since the clinical result is excellent, this finding could be a breakthrough in testicular cancer study. A cellular communication between different cancer cell type through chemokine which could affect response to chemotherapy. CONCLUSION: Treatment with surgery and chemotherapy is well tolerated and received. A further specific clinical study needs to be performed to investigate this finding in the future. |
format | Online Article Text |
id | pubmed-9840355 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-98403552023-01-15 Bilateral synchronous testicular cancer: A case report Ginting, Jeremy Thompson Sihombing, Bungaran Warli, Syah Mirsya Siregar, Ginanda Putra Prapiska, Fauriski Febrian Int J Surg Case Rep Case Report INTRODUCTION AND IMPORTANCE: Testicular cancer is the most common type of malignancy in young adult males, accounting for 1 % of all cancer diagnosis in men and 5 % of all urologic tumors. It is one of the malignancies with the highest cure rate. Bilateral germ cell tumor of the testicles is rare, representing only 1 % of all new cases of testicular cancer, around 30 % of which occur synchronously. Interestingly, there is not yet an occurrence where the bilateral synchronous testicular cancer has different histopathological type. CASE PRESENTATION: In this paper, we performed bilateral radical orchiectomy in different occasion, followed by adjuvant chemotherapy (BEP regiment). CLINICAL DISCUSSION: Since the clinical result is excellent, this finding could be a breakthrough in testicular cancer study. A cellular communication between different cancer cell type through chemokine which could affect response to chemotherapy. CONCLUSION: Treatment with surgery and chemotherapy is well tolerated and received. A further specific clinical study needs to be performed to investigate this finding in the future. Elsevier 2023-01-04 /pmc/articles/PMC9840355/ /pubmed/36640464 http://dx.doi.org/10.1016/j.ijscr.2022.107870 Text en © 2023 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Case Report Ginting, Jeremy Thompson Sihombing, Bungaran Warli, Syah Mirsya Siregar, Ginanda Putra Prapiska, Fauriski Febrian Bilateral synchronous testicular cancer: A case report |
title | Bilateral synchronous testicular cancer: A case report |
title_full | Bilateral synchronous testicular cancer: A case report |
title_fullStr | Bilateral synchronous testicular cancer: A case report |
title_full_unstemmed | Bilateral synchronous testicular cancer: A case report |
title_short | Bilateral synchronous testicular cancer: A case report |
title_sort | bilateral synchronous testicular cancer: a case report |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840355/ https://www.ncbi.nlm.nih.gov/pubmed/36640464 http://dx.doi.org/10.1016/j.ijscr.2022.107870 |
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