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Bilateral synchronous testicular cancer: A case report

INTRODUCTION AND IMPORTANCE: Testicular cancer is the most common type of malignancy in young adult males, accounting for 1 % of all cancer diagnosis in men and 5 % of all urologic tumors. It is one of the malignancies with the highest cure rate. Bilateral germ cell tumor of the testicles is rare, r...

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Autores principales: Ginting, Jeremy Thompson, Sihombing, Bungaran, Warli, Syah Mirsya, Siregar, Ginanda Putra, Prapiska, Fauriski Febrian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840355/
https://www.ncbi.nlm.nih.gov/pubmed/36640464
http://dx.doi.org/10.1016/j.ijscr.2022.107870
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author Ginting, Jeremy Thompson
Sihombing, Bungaran
Warli, Syah Mirsya
Siregar, Ginanda Putra
Prapiska, Fauriski Febrian
author_facet Ginting, Jeremy Thompson
Sihombing, Bungaran
Warli, Syah Mirsya
Siregar, Ginanda Putra
Prapiska, Fauriski Febrian
author_sort Ginting, Jeremy Thompson
collection PubMed
description INTRODUCTION AND IMPORTANCE: Testicular cancer is the most common type of malignancy in young adult males, accounting for 1 % of all cancer diagnosis in men and 5 % of all urologic tumors. It is one of the malignancies with the highest cure rate. Bilateral germ cell tumor of the testicles is rare, representing only 1 % of all new cases of testicular cancer, around 30 % of which occur synchronously. Interestingly, there is not yet an occurrence where the bilateral synchronous testicular cancer has different histopathological type. CASE PRESENTATION: In this paper, we performed bilateral radical orchiectomy in different occasion, followed by adjuvant chemotherapy (BEP regiment). CLINICAL DISCUSSION: Since the clinical result is excellent, this finding could be a breakthrough in testicular cancer study. A cellular communication between different cancer cell type through chemokine which could affect response to chemotherapy. CONCLUSION: Treatment with surgery and chemotherapy is well tolerated and received. A further specific clinical study needs to be performed to investigate this finding in the future.
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spelling pubmed-98403552023-01-15 Bilateral synchronous testicular cancer: A case report Ginting, Jeremy Thompson Sihombing, Bungaran Warli, Syah Mirsya Siregar, Ginanda Putra Prapiska, Fauriski Febrian Int J Surg Case Rep Case Report INTRODUCTION AND IMPORTANCE: Testicular cancer is the most common type of malignancy in young adult males, accounting for 1 % of all cancer diagnosis in men and 5 % of all urologic tumors. It is one of the malignancies with the highest cure rate. Bilateral germ cell tumor of the testicles is rare, representing only 1 % of all new cases of testicular cancer, around 30 % of which occur synchronously. Interestingly, there is not yet an occurrence where the bilateral synchronous testicular cancer has different histopathological type. CASE PRESENTATION: In this paper, we performed bilateral radical orchiectomy in different occasion, followed by adjuvant chemotherapy (BEP regiment). CLINICAL DISCUSSION: Since the clinical result is excellent, this finding could be a breakthrough in testicular cancer study. A cellular communication between different cancer cell type through chemokine which could affect response to chemotherapy. CONCLUSION: Treatment with surgery and chemotherapy is well tolerated and received. A further specific clinical study needs to be performed to investigate this finding in the future. Elsevier 2023-01-04 /pmc/articles/PMC9840355/ /pubmed/36640464 http://dx.doi.org/10.1016/j.ijscr.2022.107870 Text en © 2023 The Authors https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Ginting, Jeremy Thompson
Sihombing, Bungaran
Warli, Syah Mirsya
Siregar, Ginanda Putra
Prapiska, Fauriski Febrian
Bilateral synchronous testicular cancer: A case report
title Bilateral synchronous testicular cancer: A case report
title_full Bilateral synchronous testicular cancer: A case report
title_fullStr Bilateral synchronous testicular cancer: A case report
title_full_unstemmed Bilateral synchronous testicular cancer: A case report
title_short Bilateral synchronous testicular cancer: A case report
title_sort bilateral synchronous testicular cancer: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840355/
https://www.ncbi.nlm.nih.gov/pubmed/36640464
http://dx.doi.org/10.1016/j.ijscr.2022.107870
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