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Congenital Pseudoarthrosis of the Tibia: A Narrative Review

Congenital pseudoarthrosis of the tibia, also known as CPT, is a rare bone disease mostly occurring in the pediatric age group of 10. The case generally represents anterolateral bowing of the tibia with refractures. This condition is quite rare and has very few cases per year. CPT is still a challen...

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Autores principales: Banchhor, Hansika, Chimurkar, Vilas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840411/
https://www.ncbi.nlm.nih.gov/pubmed/36654595
http://dx.doi.org/10.7759/cureus.32501
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author Banchhor, Hansika
Chimurkar, Vilas
author_facet Banchhor, Hansika
Chimurkar, Vilas
author_sort Banchhor, Hansika
collection PubMed
description Congenital pseudoarthrosis of the tibia, also known as CPT, is a rare bone disease mostly occurring in the pediatric age group of 10. The case generally represents anterolateral bowing of the tibia with refractures. This condition is quite rare and has very few cases per year. CPT is still a challenging concern in orthopedics. Bone reunion often requires repeated surgical measurements. With advancements, we have new treatment plans that include induced membrane techniques and bone marrow stromal cell grafts of various induced and morphogenetic protein, which still requires confirmation. Different treatment strategies based on surgical, mechanical, and biological concepts have been shown with varying success rates. Ilizarov technique and vascularised fibular grafts have vastly increased the effectiveness in treating CPT of the tibia. Constant and recurrent refracture, residual deformities, and difficulty obtaining bone union remain the challenges in managing CPT. Hence, phasing CPT as bowing the tibia in an anterolateral fashion is more appropriate because it’s a heterogeneous entity with varying prognoses.
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spelling pubmed-98404112023-01-17 Congenital Pseudoarthrosis of the Tibia: A Narrative Review Banchhor, Hansika Chimurkar, Vilas Cureus Radiology Congenital pseudoarthrosis of the tibia, also known as CPT, is a rare bone disease mostly occurring in the pediatric age group of 10. The case generally represents anterolateral bowing of the tibia with refractures. This condition is quite rare and has very few cases per year. CPT is still a challenging concern in orthopedics. Bone reunion often requires repeated surgical measurements. With advancements, we have new treatment plans that include induced membrane techniques and bone marrow stromal cell grafts of various induced and morphogenetic protein, which still requires confirmation. Different treatment strategies based on surgical, mechanical, and biological concepts have been shown with varying success rates. Ilizarov technique and vascularised fibular grafts have vastly increased the effectiveness in treating CPT of the tibia. Constant and recurrent refracture, residual deformities, and difficulty obtaining bone union remain the challenges in managing CPT. Hence, phasing CPT as bowing the tibia in an anterolateral fashion is more appropriate because it’s a heterogeneous entity with varying prognoses. Cureus 2022-12-14 /pmc/articles/PMC9840411/ /pubmed/36654595 http://dx.doi.org/10.7759/cureus.32501 Text en Copyright © 2022, Banchhor et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Radiology
Banchhor, Hansika
Chimurkar, Vilas
Congenital Pseudoarthrosis of the Tibia: A Narrative Review
title Congenital Pseudoarthrosis of the Tibia: A Narrative Review
title_full Congenital Pseudoarthrosis of the Tibia: A Narrative Review
title_fullStr Congenital Pseudoarthrosis of the Tibia: A Narrative Review
title_full_unstemmed Congenital Pseudoarthrosis of the Tibia: A Narrative Review
title_short Congenital Pseudoarthrosis of the Tibia: A Narrative Review
title_sort congenital pseudoarthrosis of the tibia: a narrative review
topic Radiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840411/
https://www.ncbi.nlm.nih.gov/pubmed/36654595
http://dx.doi.org/10.7759/cureus.32501
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