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Immunohistochemical Localization of Alogliptin, a DPP-4 Inhibitor, in Tissues of Normal and Type 2 Diabetes Model Rat

We investigated the pharmacokinetics of alogliptin (AG) at the cell and tissue level in healthy Wistar rats and a type 2 diabetic Goto-Kakizaki (GK) rat model. Immunohistochemistry of the renal tissue in these rats, post 1 hr of AG administration, showed that the signal was observed in the glomeruli...

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Detalles Bibliográficos
Autores principales:	Yamamoto, Yutaro, Ura, Kanae, Matsukawa, Takuma, Saita, Tetsuya, Shin, Masashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	JAPAN SOCIETY OF HISTOCHEMISTRY AND CYTOCHEMISTRY 2022
Materias:	Regular Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840470/ https://www.ncbi.nlm.nih.gov/pubmed/36688140 http://dx.doi.org/10.1267/ahc.22-00032

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