Three Adult Cases of STAT1 Gain-of-Function with Chronic Mucocutaneous Candidiasis Treated with JAK Inhibitors

PURPOSE: The aim of this study was to characterize clinical effects and biomarkers in three patients with chronic mucocutaneous candidiasis (CMC) caused by gain-of-function (GOF) mutations in the STAT1 gene during treatment with Janus kinase (JAK) inhibitors. METHODS: Mass cytometry (CyTOF) was used...

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Detalles Bibliográficos
Autores principales: Borgström, Emilie W., Edvinsson, Marie, Pérez, Lucía P., Norlin, Anna C., Enoksson, Sara L., Hansen, Susanne, Fasth, Anders, Friman, Vanda, Kämpe, Olle, Månsson, Robert, Estupiñán, Hernando Y., Wang, Qing, Ziyang, Tan, Lakshmikanth, Tadepally, Smith, Carl Inge E., Brodin, Petter, Bergman, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840596/
https://www.ncbi.nlm.nih.gov/pubmed/36050429
http://dx.doi.org/10.1007/s10875-022-01351-0

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