Cargando…

Antibiotic-sterol interactions provide insight into the selectivity of natural aromatic analogues of amphotericin B and their photoisomers

Aromatic heptaene macrolides (AHMs) belong to the group of polyene macrolide antifungal antibiotics. Members of this group were the first to be used in the treatment of systemic fungal infections. Amphotericin B (AmB), a non-aromatic representative of heptaene macrolides, is of significant clinical...

Descripción completa

Detalles Bibliográficos
Autores principales: Borzyszkowska-Bukowska, Julia, Czub, Jacek, Szczeblewski, Paweł, Laskowski, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840637/
https://www.ncbi.nlm.nih.gov/pubmed/36641464
http://dx.doi.org/10.1038/s41598-023-28036-x