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The Efficacy of Conservative Management in Uncomplicated Acute Appendicitis - A Single-Center Retrospective Study

Background Acute appendicitis remains the most common cause of lower abdominal pain leading to emergency visits. Even though the standard treatment of acute appendicitis remains appendectomy, in recent times, multiple randomized control trials and meta-analyses have deduced conservative treatment as...

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Autores principales: Akbar, Hira F, Kareem, Talha, Saleem, Nitasha, Seerat, Muhammad I, Hussain, M. Irshad, Javed, Irfan, Muhammad Ali, Syed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840891/
https://www.ncbi.nlm.nih.gov/pubmed/36654610
http://dx.doi.org/10.7759/cureus.32606
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author Akbar, Hira F
Kareem, Talha
Saleem, Nitasha
Seerat, Muhammad I
Hussain, M. Irshad
Javed, Irfan
Muhammad Ali, Syed
author_facet Akbar, Hira F
Kareem, Talha
Saleem, Nitasha
Seerat, Muhammad I
Hussain, M. Irshad
Javed, Irfan
Muhammad Ali, Syed
author_sort Akbar, Hira F
collection PubMed
description Background Acute appendicitis remains the most common cause of lower abdominal pain leading to emergency visits. Even though the standard treatment of acute appendicitis remains appendectomy, in recent times, multiple randomized control trials and meta-analyses have deduced conservative treatment as a successful alternative treatment. During the coronavirus disease (COVID) pandemic, with a shortage of staff and resources, treatment with conservative management of uncomplicated acute appendicitis became very beneficial under certain circumstances and conditions. This study aimed to assess whether it is effective to manage patients with uncomplicated acute appendicitis with antibiotic therapy. Methodology This was a single hospital based retrospective, cross-sectional study from Jan 2015 to May 2020. Patients with clinical and radiological features of uncomplicated acute appendicitis with Alvarado's score >6 were included in the study. Patients were kept on antibiotics, intravenous fluids, and analgesia as part of a conservative regime. Those who failed to respond to conservative therapy were managed surgically. The follow-up period was six months. Results One hundred eighty-two cases of uncomplicated acute appendicitis were included and managed conservatively, of which 52.2% were males while 47.8% were females. The median age of the patients was 26 years. Conservative treatment was successful in 26.2% of the patients, with a recurrence of 5.5% in the six-month follow-up period. The mean number of days of hospital stay was three days in patients treated with conservative or surgical treatment. Conclusion Conservative management is gaining popularity, and many centers are inclined towards non-operative management; however, appendectomy remains the gold standard treatment for appendicitis.
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spelling pubmed-98408912023-01-17 The Efficacy of Conservative Management in Uncomplicated Acute Appendicitis - A Single-Center Retrospective Study Akbar, Hira F Kareem, Talha Saleem, Nitasha Seerat, Muhammad I Hussain, M. Irshad Javed, Irfan Muhammad Ali, Syed Cureus General Surgery Background Acute appendicitis remains the most common cause of lower abdominal pain leading to emergency visits. Even though the standard treatment of acute appendicitis remains appendectomy, in recent times, multiple randomized control trials and meta-analyses have deduced conservative treatment as a successful alternative treatment. During the coronavirus disease (COVID) pandemic, with a shortage of staff and resources, treatment with conservative management of uncomplicated acute appendicitis became very beneficial under certain circumstances and conditions. This study aimed to assess whether it is effective to manage patients with uncomplicated acute appendicitis with antibiotic therapy. Methodology This was a single hospital based retrospective, cross-sectional study from Jan 2015 to May 2020. Patients with clinical and radiological features of uncomplicated acute appendicitis with Alvarado's score >6 were included in the study. Patients were kept on antibiotics, intravenous fluids, and analgesia as part of a conservative regime. Those who failed to respond to conservative therapy were managed surgically. The follow-up period was six months. Results One hundred eighty-two cases of uncomplicated acute appendicitis were included and managed conservatively, of which 52.2% were males while 47.8% were females. The median age of the patients was 26 years. Conservative treatment was successful in 26.2% of the patients, with a recurrence of 5.5% in the six-month follow-up period. The mean number of days of hospital stay was three days in patients treated with conservative or surgical treatment. Conclusion Conservative management is gaining popularity, and many centers are inclined towards non-operative management; however, appendectomy remains the gold standard treatment for appendicitis. Cureus 2022-12-16 /pmc/articles/PMC9840891/ /pubmed/36654610 http://dx.doi.org/10.7759/cureus.32606 Text en Copyright © 2022, Akbar et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle General Surgery
Akbar, Hira F
Kareem, Talha
Saleem, Nitasha
Seerat, Muhammad I
Hussain, M. Irshad
Javed, Irfan
Muhammad Ali, Syed
The Efficacy of Conservative Management in Uncomplicated Acute Appendicitis - A Single-Center Retrospective Study
title The Efficacy of Conservative Management in Uncomplicated Acute Appendicitis - A Single-Center Retrospective Study
title_full The Efficacy of Conservative Management in Uncomplicated Acute Appendicitis - A Single-Center Retrospective Study
title_fullStr The Efficacy of Conservative Management in Uncomplicated Acute Appendicitis - A Single-Center Retrospective Study
title_full_unstemmed The Efficacy of Conservative Management in Uncomplicated Acute Appendicitis - A Single-Center Retrospective Study
title_short The Efficacy of Conservative Management in Uncomplicated Acute Appendicitis - A Single-Center Retrospective Study
title_sort efficacy of conservative management in uncomplicated acute appendicitis - a single-center retrospective study
topic General Surgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840891/
https://www.ncbi.nlm.nih.gov/pubmed/36654610
http://dx.doi.org/10.7759/cureus.32606
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