Supervised chemical graph mining improves drug-induced liver injury prediction

Drug-induced liver injury (DILI) is the main cause of drug failure in clinical trials. The characterization of toxic compounds in terms of chemical structure is important because compounds can be metabolized to toxic substances in the liver. Traditional machine learning approaches have had limited s...

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Detalles Bibliográficos
Autores principales: Lim, Sangsoo, Kim, Youngkuk, Gu, Jeonghyeon, Lee, Sunho, Shin, Wonseok, Kim, Sun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840932/
https://www.ncbi.nlm.nih.gov/pubmed/36654861
http://dx.doi.org/10.1016/j.isci.2022.105677

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840932/
https://www.ncbi.nlm.nih.gov/pubmed/36654861
http://dx.doi.org/10.1016/j.isci.2022.105677

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