Downregulation of UBE4B promotes CNS axon regrowth and functional recovery after stroke

The limited intrinsic regrowth capacity of corticospinal axons impedes functional recovery after cortical stroke. Although the mammalian target of rapamycin (mTOR) and p53 pathways have been identified as the key intrinsic pathways regulating CNS axon regrowth, little is known about the key upstream...

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Detalles Bibliográficos
Autores principales: Jin, Shuang, Chen, Xiangfeng, Zheng, Hanyu, Cai, Wanxiong, Lin, Xurong, Kong, Xiangxing, Ni, Yingchun, Ye, Jingjia, Li, Xiaodan, Shen, Luoan, Guo, Binjie, Abdelrahman, Zeinab, Zhou, Songlin, Mao, Susu, Wang, Yaxian, Yao, Chun, Gu, Xiaosong, Yu, Bin, Wang, Zhiping, Wang, Xuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840934/
https://www.ncbi.nlm.nih.gov/pubmed/36654858
http://dx.doi.org/10.1016/j.isci.2022.105885

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