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Liver Abscess caused by Cytomegalovirus in a Patient with Acquired Immunodeficiency Syndrome

Cytomegalovirus (CMV) causes severe infection in immunocompromised patients, especially those with acquired immunodeficiency syndrome (AIDS), those who have undergone organ transplantation, and/or those who are being treated with steroids. In patients with AIDS, CMV is the most common pathogen that...

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Autores principales: Lee, Jin Young, Park, Jong woo, Park, Ji Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Infectious Diseases and Korean Society for Chemotherapy 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840953/
https://www.ncbi.nlm.nih.gov/pubmed/32869553
http://dx.doi.org/10.3947/ic.2020.0206
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author Lee, Jin Young
Park, Jong woo
Park, Ji Young
author_facet Lee, Jin Young
Park, Jong woo
Park, Ji Young
author_sort Lee, Jin Young
collection PubMed
description Cytomegalovirus (CMV) causes severe infection in immunocompromised patients, especially those with acquired immunodeficiency syndrome (AIDS), those who have undergone organ transplantation, and/or those who are being treated with steroids. In patients with AIDS, CMV is the most common pathogen that causes opportunistic infections. Here, we present a case of liver abscess due to CMV in a 58-year-old man diagnosed with AIDS. At the time of the study, his CD4 T lymphocyte count was 39 cells/mm(3), and his human immunodeficiency virus (HIV) ribonucleic acid (RNA) level was 411,000 copies/mL. Upon presentation, he complained of upper abdominal pain. Ultrasonography-guided percutaneous drainage of the liver abscess was performed, and polymerase chain reaction analysis of the drained pus was positive for CMV. He was treated with intravenous ganciclovir, after which he recovered fully. In conclusion, our patient represents, to our knowledge, the first described case of liver abscess caused by CMV in an AIDS patient, which was probably facilitated by severe immunodeficiency.
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spelling pubmed-98409532023-01-30 Liver Abscess caused by Cytomegalovirus in a Patient with Acquired Immunodeficiency Syndrome Lee, Jin Young Park, Jong woo Park, Ji Young Infect Chemother Case Report Cytomegalovirus (CMV) causes severe infection in immunocompromised patients, especially those with acquired immunodeficiency syndrome (AIDS), those who have undergone organ transplantation, and/or those who are being treated with steroids. In patients with AIDS, CMV is the most common pathogen that causes opportunistic infections. Here, we present a case of liver abscess due to CMV in a 58-year-old man diagnosed with AIDS. At the time of the study, his CD4 T lymphocyte count was 39 cells/mm(3), and his human immunodeficiency virus (HIV) ribonucleic acid (RNA) level was 411,000 copies/mL. Upon presentation, he complained of upper abdominal pain. Ultrasonography-guided percutaneous drainage of the liver abscess was performed, and polymerase chain reaction analysis of the drained pus was positive for CMV. He was treated with intravenous ganciclovir, after which he recovered fully. In conclusion, our patient represents, to our knowledge, the first described case of liver abscess caused by CMV in an AIDS patient, which was probably facilitated by severe immunodeficiency. The Korean Society of Infectious Diseases and Korean Society for Chemotherapy 2022-12 2020-08-12 /pmc/articles/PMC9840953/ /pubmed/32869553 http://dx.doi.org/10.3947/ic.2020.0206 Text en Copyright © 2022 by The Korean Society of Infectious Diseases, Korean Society for Antimicrobial Therapy, and The Korean Society for AIDS https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Lee, Jin Young
Park, Jong woo
Park, Ji Young
Liver Abscess caused by Cytomegalovirus in a Patient with Acquired Immunodeficiency Syndrome
title Liver Abscess caused by Cytomegalovirus in a Patient with Acquired Immunodeficiency Syndrome
title_full Liver Abscess caused by Cytomegalovirus in a Patient with Acquired Immunodeficiency Syndrome
title_fullStr Liver Abscess caused by Cytomegalovirus in a Patient with Acquired Immunodeficiency Syndrome
title_full_unstemmed Liver Abscess caused by Cytomegalovirus in a Patient with Acquired Immunodeficiency Syndrome
title_short Liver Abscess caused by Cytomegalovirus in a Patient with Acquired Immunodeficiency Syndrome
title_sort liver abscess caused by cytomegalovirus in a patient with acquired immunodeficiency syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9840953/
https://www.ncbi.nlm.nih.gov/pubmed/32869553
http://dx.doi.org/10.3947/ic.2020.0206
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