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Occupational Lung Disease Caused by Exposure to Polytetrafluoroethylene

We herein report a 45-year-old-man with multiple foreign body granulomas in the lungs caused by polytetrafluoroethylene (PTFE). A mass in the right lower lobe of the lung and bilateral centrilobular lung nodules were found unexpectedly during the patient's visit to a hospital for a respiratory...

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Detalles Bibliográficos
Autores principales: Aoki, Ami, Saito, Akira, Shima, Kenjiro, Kimura, Yosuke, Asakawa, Katsuaki, Ohashi, Riuko, Umezu, Hajime, Sakagami, Takuro, Moriyama, Hiroshi, Kikuchi, Toshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841090/
https://www.ncbi.nlm.nih.gov/pubmed/35598992
http://dx.doi.org/10.2169/internalmedicine.9008-21
Descripción
Sumario:We herein report a 45-year-old-man with multiple foreign body granulomas in the lungs caused by polytetrafluoroethylene (PTFE). A mass in the right lower lobe of the lung and bilateral centrilobular lung nodules were found unexpectedly during the patient's visit to a hospital for a respiratory infection. The patient's occupation for 26 years involved spraying PTFE. A lung biopsy using bronchoscopy revealed granulomatous lesions and giant cells. The presence of fluorine in the granulomatous lesions was confirmed using an electron probe microanalyzer with wavelength dispersive spectrometer. Fluorine is a component of PTFE and is not found in normal lung tissue.