Occupational Lung Disease Caused by Exposure to Polytetrafluoroethylene

We herein report a 45-year-old-man with multiple foreign body granulomas in the lungs caused by polytetrafluoroethylene (PTFE). A mass in the right lower lobe of the lung and bilateral centrilobular lung nodules were found unexpectedly during the patient's visit to a hospital for a respiratory...

Descripción completa

Detalles Bibliográficos
Autores principales: Aoki, Ami, Saito, Akira, Shima, Kenjiro, Kimura, Yosuke, Asakawa, Katsuaki, Ohashi, Riuko, Umezu, Hajime, Sakagami, Takuro, Moriyama, Hiroshi, Kikuchi, Toshiaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841090/
https://www.ncbi.nlm.nih.gov/pubmed/35598992
http://dx.doi.org/10.2169/internalmedicine.9008-21
_version_ 1784869755213053952
author Aoki, Ami
Saito, Akira
Shima, Kenjiro
Kimura, Yosuke
Asakawa, Katsuaki
Ohashi, Riuko
Umezu, Hajime
Sakagami, Takuro
Moriyama, Hiroshi
Kikuchi, Toshiaki
author_facet Aoki, Ami
Saito, Akira
Shima, Kenjiro
Kimura, Yosuke
Asakawa, Katsuaki
Ohashi, Riuko
Umezu, Hajime
Sakagami, Takuro
Moriyama, Hiroshi
Kikuchi, Toshiaki
author_sort Aoki, Ami
collection PubMed
description We herein report a 45-year-old-man with multiple foreign body granulomas in the lungs caused by polytetrafluoroethylene (PTFE). A mass in the right lower lobe of the lung and bilateral centrilobular lung nodules were found unexpectedly during the patient's visit to a hospital for a respiratory infection. The patient's occupation for 26 years involved spraying PTFE. A lung biopsy using bronchoscopy revealed granulomatous lesions and giant cells. The presence of fluorine in the granulomatous lesions was confirmed using an electron probe microanalyzer with wavelength dispersive spectrometer. Fluorine is a component of PTFE and is not found in normal lung tissue.
format Online
Article
Text
id pubmed-9841090
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher The Japanese Society of Internal Medicine
record_format MEDLINE/PubMed
spelling pubmed-98410902023-01-26 Occupational Lung Disease Caused by Exposure to Polytetrafluoroethylene Aoki, Ami Saito, Akira Shima, Kenjiro Kimura, Yosuke Asakawa, Katsuaki Ohashi, Riuko Umezu, Hajime Sakagami, Takuro Moriyama, Hiroshi Kikuchi, Toshiaki Intern Med Case Report We herein report a 45-year-old-man with multiple foreign body granulomas in the lungs caused by polytetrafluoroethylene (PTFE). A mass in the right lower lobe of the lung and bilateral centrilobular lung nodules were found unexpectedly during the patient's visit to a hospital for a respiratory infection. The patient's occupation for 26 years involved spraying PTFE. A lung biopsy using bronchoscopy revealed granulomatous lesions and giant cells. The presence of fluorine in the granulomatous lesions was confirmed using an electron probe microanalyzer with wavelength dispersive spectrometer. Fluorine is a component of PTFE and is not found in normal lung tissue. The Japanese Society of Internal Medicine 2022-05-21 2022-12-15 /pmc/articles/PMC9841090/ /pubmed/35598992 http://dx.doi.org/10.2169/internalmedicine.9008-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Aoki, Ami
Saito, Akira
Shima, Kenjiro
Kimura, Yosuke
Asakawa, Katsuaki
Ohashi, Riuko
Umezu, Hajime
Sakagami, Takuro
Moriyama, Hiroshi
Kikuchi, Toshiaki
Occupational Lung Disease Caused by Exposure to Polytetrafluoroethylene
title Occupational Lung Disease Caused by Exposure to Polytetrafluoroethylene
title_full Occupational Lung Disease Caused by Exposure to Polytetrafluoroethylene
title_fullStr Occupational Lung Disease Caused by Exposure to Polytetrafluoroethylene
title_full_unstemmed Occupational Lung Disease Caused by Exposure to Polytetrafluoroethylene
title_short Occupational Lung Disease Caused by Exposure to Polytetrafluoroethylene
title_sort occupational lung disease caused by exposure to polytetrafluoroethylene
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841090/
https://www.ncbi.nlm.nih.gov/pubmed/35598992
http://dx.doi.org/10.2169/internalmedicine.9008-21
work_keys_str_mv AT aokiami occupationallungdiseasecausedbyexposuretopolytetrafluoroethylene
AT saitoakira occupationallungdiseasecausedbyexposuretopolytetrafluoroethylene
AT shimakenjiro occupationallungdiseasecausedbyexposuretopolytetrafluoroethylene
AT kimurayosuke occupationallungdiseasecausedbyexposuretopolytetrafluoroethylene
AT asakawakatsuaki occupationallungdiseasecausedbyexposuretopolytetrafluoroethylene
AT ohashiriuko occupationallungdiseasecausedbyexposuretopolytetrafluoroethylene
AT umezuhajime occupationallungdiseasecausedbyexposuretopolytetrafluoroethylene
AT sakagamitakuro occupationallungdiseasecausedbyexposuretopolytetrafluoroethylene
AT moriyamahiroshi occupationallungdiseasecausedbyexposuretopolytetrafluoroethylene
AT kikuchitoshiaki occupationallungdiseasecausedbyexposuretopolytetrafluoroethylene

Ejemplares similares