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The Visceral-to-subcutaneous Adipose Tissue Area Ratio Is Associated with Retreatment in Chronic Pancreatitis Patients with Pancreatolithiasis after Extracorporeal Shock Wave Lithotripsy

OBJECTIVE: Extracorporeal shock wave lithotripsy (ESWL) has been used to treat pancreatolithiasis in patients with chronic pancreatitis (CP), but the high recurrence rate remains challenging. We therefore evaluated the association between body composition parameters and the prediction of retreatment...

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Autores principales: Yokoyama, Kunihiko, Takamura, Masaaki, Watanabe, Jun, Nakamura, Atsuo, Sato, Yuichi, Sekine, Atsuo, Terai, Shuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841102/
https://www.ncbi.nlm.nih.gov/pubmed/35650122
http://dx.doi.org/10.2169/internalmedicine.9038-21
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author Yokoyama, Kunihiko
Takamura, Masaaki
Watanabe, Jun
Nakamura, Atsuo
Sato, Yuichi
Sekine, Atsuo
Terai, Shuji
author_facet Yokoyama, Kunihiko
Takamura, Masaaki
Watanabe, Jun
Nakamura, Atsuo
Sato, Yuichi
Sekine, Atsuo
Terai, Shuji
author_sort Yokoyama, Kunihiko
collection PubMed
description OBJECTIVE: Extracorporeal shock wave lithotripsy (ESWL) has been used to treat pancreatolithiasis in patients with chronic pancreatitis (CP), but the high recurrence rate remains challenging. We therefore evaluated the association between body composition parameters and the prediction of retreatment after ESWL. METHODS: This study retrospectively evaluated 42 patients with CP who had been treated with ESWL between 2008 and 2019 in a single center. Body composition parameters were measured on pretreatment computed tomography images. Patients who underwent repeat ESWL were classified as the retreatment group. RESULTS: There were 13 (31.0%) and 29 (69.0%) patients in the retreatment and non-retreatment groups, respectively. The visceral-to-subcutaneous adipose tissue area ratio (VSR) of the retreatment group was significantly lower than that of the non-retreatment group (p=0.016). When divided by the median VSR, 10 of the 20 patients with a VSR of <0.85 underwent retreatment, whereas 3 of the 22 patients with a VSR of ≥0.85 underwent retreatment (p=0.019). According to a multivariate analysis, the VSR (p=0.010) and age (p=0.037) were independent factors associated with retreatment after ESWL. CONCLUSION: This study showed that the VSR can predict the retreatment of patients with CP after ESWL.
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spelling pubmed-98411022023-01-26 The Visceral-to-subcutaneous Adipose Tissue Area Ratio Is Associated with Retreatment in Chronic Pancreatitis Patients with Pancreatolithiasis after Extracorporeal Shock Wave Lithotripsy Yokoyama, Kunihiko Takamura, Masaaki Watanabe, Jun Nakamura, Atsuo Sato, Yuichi Sekine, Atsuo Terai, Shuji Intern Med Original Article OBJECTIVE: Extracorporeal shock wave lithotripsy (ESWL) has been used to treat pancreatolithiasis in patients with chronic pancreatitis (CP), but the high recurrence rate remains challenging. We therefore evaluated the association between body composition parameters and the prediction of retreatment after ESWL. METHODS: This study retrospectively evaluated 42 patients with CP who had been treated with ESWL between 2008 and 2019 in a single center. Body composition parameters were measured on pretreatment computed tomography images. Patients who underwent repeat ESWL were classified as the retreatment group. RESULTS: There were 13 (31.0%) and 29 (69.0%) patients in the retreatment and non-retreatment groups, respectively. The visceral-to-subcutaneous adipose tissue area ratio (VSR) of the retreatment group was significantly lower than that of the non-retreatment group (p=0.016). When divided by the median VSR, 10 of the 20 patients with a VSR of <0.85 underwent retreatment, whereas 3 of the 22 patients with a VSR of ≥0.85 underwent retreatment (p=0.019). According to a multivariate analysis, the VSR (p=0.010) and age (p=0.037) were independent factors associated with retreatment after ESWL. CONCLUSION: This study showed that the VSR can predict the retreatment of patients with CP after ESWL. The Japanese Society of Internal Medicine 2022-05-31 2022-12-15 /pmc/articles/PMC9841102/ /pubmed/35650122 http://dx.doi.org/10.2169/internalmedicine.9038-21 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Original Article
Yokoyama, Kunihiko
Takamura, Masaaki
Watanabe, Jun
Nakamura, Atsuo
Sato, Yuichi
Sekine, Atsuo
Terai, Shuji
The Visceral-to-subcutaneous Adipose Tissue Area Ratio Is Associated with Retreatment in Chronic Pancreatitis Patients with Pancreatolithiasis after Extracorporeal Shock Wave Lithotripsy
title The Visceral-to-subcutaneous Adipose Tissue Area Ratio Is Associated with Retreatment in Chronic Pancreatitis Patients with Pancreatolithiasis after Extracorporeal Shock Wave Lithotripsy
title_full The Visceral-to-subcutaneous Adipose Tissue Area Ratio Is Associated with Retreatment in Chronic Pancreatitis Patients with Pancreatolithiasis after Extracorporeal Shock Wave Lithotripsy
title_fullStr The Visceral-to-subcutaneous Adipose Tissue Area Ratio Is Associated with Retreatment in Chronic Pancreatitis Patients with Pancreatolithiasis after Extracorporeal Shock Wave Lithotripsy
title_full_unstemmed The Visceral-to-subcutaneous Adipose Tissue Area Ratio Is Associated with Retreatment in Chronic Pancreatitis Patients with Pancreatolithiasis after Extracorporeal Shock Wave Lithotripsy
title_short The Visceral-to-subcutaneous Adipose Tissue Area Ratio Is Associated with Retreatment in Chronic Pancreatitis Patients with Pancreatolithiasis after Extracorporeal Shock Wave Lithotripsy
title_sort visceral-to-subcutaneous adipose tissue area ratio is associated with retreatment in chronic pancreatitis patients with pancreatolithiasis after extracorporeal shock wave lithotripsy
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841102/
https://www.ncbi.nlm.nih.gov/pubmed/35650122
http://dx.doi.org/10.2169/internalmedicine.9038-21
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