Sansoninto-induced Lung Injury

A man in his 70s visited our department for dyspnea with pulmonary infiltrate that was unresolved by antibiotics. He had been taking Sansoninto for five years and doubled its dose a month ago. After discontinuing Sansoninto without any additional medications, his symptoms gradually disappeared, and...

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Detalles Bibliográficos
Autores principales: Komiya, Kosaku, Mitsui, Marcelo Takahiro, Watanabe, Toru, Nasu, Masaru, Hiramatsu, Kazufumi, Kadota, Jun-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841115/
https://www.ncbi.nlm.nih.gov/pubmed/35569994
http://dx.doi.org/10.2169/internalmedicine.9747-22
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author Komiya, Kosaku
Mitsui, Marcelo Takahiro
Watanabe, Toru
Nasu, Masaru
Hiramatsu, Kazufumi
Kadota, Jun-ichi
author_facet Komiya, Kosaku
Mitsui, Marcelo Takahiro
Watanabe, Toru
Nasu, Masaru
Hiramatsu, Kazufumi
Kadota, Jun-ichi
author_sort Komiya, Kosaku
collection PubMed
description A man in his 70s visited our department for dyspnea with pulmonary infiltrate that was unresolved by antibiotics. He had been taking Sansoninto for five years and doubled its dose a month ago. After discontinuing Sansoninto without any additional medications, his symptoms gradually disappeared, and pulmonary infiltration improved. Drug lymphocyte stimulation tests showed a positive result for Sansoninto. We diagnosed this patient with Sansoninto-induced lung injury. Sansoninto is a combination drug that consists of sansonin, bukuryo, senkyo, chimo, and kanzo. This paper reports the first case of Sansoninto-induced lung injury and discusses the mechanism considering its components.
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spelling pubmed-98411152023-01-26 Sansoninto-induced Lung Injury Komiya, Kosaku Mitsui, Marcelo Takahiro Watanabe, Toru Nasu, Masaru Hiramatsu, Kazufumi Kadota, Jun-ichi Intern Med Case Report A man in his 70s visited our department for dyspnea with pulmonary infiltrate that was unresolved by antibiotics. He had been taking Sansoninto for five years and doubled its dose a month ago. After discontinuing Sansoninto without any additional medications, his symptoms gradually disappeared, and pulmonary infiltration improved. Drug lymphocyte stimulation tests showed a positive result for Sansoninto. We diagnosed this patient with Sansoninto-induced lung injury. Sansoninto is a combination drug that consists of sansonin, bukuryo, senkyo, chimo, and kanzo. This paper reports the first case of Sansoninto-induced lung injury and discusses the mechanism considering its components. The Japanese Society of Internal Medicine 2022-05-14 2022-12-15 /pmc/articles/PMC9841115/ /pubmed/35569994 http://dx.doi.org/10.2169/internalmedicine.9747-22 Text en Copyright © 2022 by The Japanese Society of Internal Medicine https://creativecommons.org/licenses/by-nc-nd/4.0/The Internal Medicine is an Open Access journal distributed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License. To view the details of this license, please visit (https://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Komiya, Kosaku
Mitsui, Marcelo Takahiro
Watanabe, Toru
Nasu, Masaru
Hiramatsu, Kazufumi
Kadota, Jun-ichi
Sansoninto-induced Lung Injury
title Sansoninto-induced Lung Injury
title_full Sansoninto-induced Lung Injury
title_fullStr Sansoninto-induced Lung Injury
title_full_unstemmed Sansoninto-induced Lung Injury
title_short Sansoninto-induced Lung Injury
title_sort sansoninto-induced lung injury
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841115/
https://www.ncbi.nlm.nih.gov/pubmed/35569994
http://dx.doi.org/10.2169/internalmedicine.9747-22
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AT watanabetoru sansonintoinducedlunginjury
AT nasumasaru sansonintoinducedlunginjury
AT hiramatsukazufumi sansonintoinducedlunginjury
AT kadotajunichi sansonintoinducedlunginjury

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