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Antigen-Dependent Inducible T-Cell Reporter System for PET Imaging of Breast Cancer and Glioblastoma

For the past several decades, chimeric antigen receptor T-cell therapies have shown promise in the treatment of cancers. These treatments would greatly benefit from companion imaging biomarkers to follow the trafficking of T cells in vivo. Methods: Using synthetic biology, we engineered T cells with...

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Detalles Bibliográficos
Autores principales: Shin, Jaehoon, Parker, Matthew F.L., Zhu, Iowis, Alanizi, Aryn, Rodriguez, Carlos I., Liu, Raymond, Watchmaker, Payal B., Kalita, Mausam, Blecha, Joseph, Luu, Justin, Wright, Brian, Lapi, Suzanne E., Flavell, Robert R., Okada, Hideho, Tlsty, Thea D., Roybal, Kole T., Wilson, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Nuclear Medicine 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841254/
https://www.ncbi.nlm.nih.gov/pubmed/35981900
http://dx.doi.org/10.2967/jnumed.122.264284