Impact of NFIB and CYP1A variants on clozapine serum concentration—A retrospective naturalistic cohort study on 526 patients with known smoking habits

Clinical response of clozapine is closely associated with serum concentration. Although tobacco smoking is the key environmental factor underlying interindividual variability in clozapine metabolism, recent genome‐wide studies suggest that CYP1A and NFIB genetic variants may also be of significant i...

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Detalles Bibliográficos
Autores principales: Lenk, Hasan Çağın, Løvsletten Smith, Robert, O'Connell, Kevin S., Jukić, Marin M., Kringen, Marianne Kristiansen, Andreassen, Ole A., Ingelman‐Sundberg, Magnus, Molden, Espen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841299/
https://www.ncbi.nlm.nih.gov/pubmed/36152308
http://dx.doi.org/10.1111/cts.13422

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