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ST3GAL5‐catalyzed gangliosides inhibit TGF‐β‐induced epithelial‐mesenchymal transition via TβRI degradation
Epithelial‐mesenchymal transition (EMT) is pivotal in the initiation and development of cancer cell metastasis. We observed that the abundance of glycosphingolipids (GSLs), especially ganglioside subtypes, decreased significantly during TGF‐β‐induced EMT in NMuMG mouse mammary epithelial cells and A...
Autores principales: | Zhang, Jing, van der Zon, Gerard, Ma, Jin, Mei, Hailiang, Cabukusta, Birol, Agaser, Cedrick C, Madunić, Katarina, Wuhrer, Manfred, Zhang, Tao, ten Dijke, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841337/ https://www.ncbi.nlm.nih.gov/pubmed/36504224 http://dx.doi.org/10.15252/embj.2021110553 |
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