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Mitochondrial related genome-wide Mendelian randomization identifies putatively causal genes for multiple cancer types

BACKGROUND: Mitochondrial dysfunction is a hallmark of cancer. However, it is unclear whether it is a cause of cancer. This two-sample Mendelian randomization (MR) analyses, uses genetic instruments to proxy the exposure of mitochondrial dysfunction and cancer summary statistics as outcomes, allowin...

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Detalles Bibliográficos
Autores principales:	Li, Yanni, Sundquist, Kristina, Zhang, Naiqi, Wang, Xiao, Sundquist, Jan, Memon, Ashfaque A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2023
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841346/ https://www.ncbi.nlm.nih.gov/pubmed/36634566 http://dx.doi.org/10.1016/j.ebiom.2022.104432

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