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Werner syndrome protein works as a dimer for unwinding and replication fork regression

The determination of the oligomeric state of functional enzymes is essential for the mechanistic understanding of their catalytic activities. RecQ helicases have diverse biochemical activities, but it is still unclear how their activities are related to their oligomeric states. We use single-molecul...

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Detalles Bibliográficos
Autores principales: Shin, Soochul, Hyun, Kwangbeom, Lee, Jinwoo, Joo, Dongwon, Kulikowicz, Tomasz, Bohr, Vilhelm A, Kim, Jaehoon, Hohng, Sungchul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841404/
https://www.ncbi.nlm.nih.gov/pubmed/36583333
http://dx.doi.org/10.1093/nar/gkac1200