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DNA–protein cross-links between abasic DNA damage and mitochondrial transcription factor A (TFAM)
In higher eukaryotic cells, mitochondria are essential organelles for energy production, metabolism, and signaling. Mitochondrial DNA (mtDNA) encodes 13 protein subunits for oxidative phosphorylation and a set of tRNAs and rRNAs. mtDNA damage, sourced from endogenous chemicals and environmental fact...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841407/ https://www.ncbi.nlm.nih.gov/pubmed/36583367 http://dx.doi.org/10.1093/nar/gkac1214 |