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RNA-guided DNA base damage repair via DNA polymerase-mediated nick translation

DNA repair is mediated by DNA synthesis guided by a DNA template. Recent studies have shown that DNA repair can also be accomplished by RNA-guided DNA synthesis. However, it remains unknown how RNA can guide DNA synthesis to repair DNA damage. In this study, we revealed the molecular mechanisms unde...

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Detalles Bibliográficos
Autores principales:	Tsegay, Pawlos S, Hernandez, Daniela, Qu, Fei, Olatunji, Mustapha, Mamun, Yasir, Chapagain, Prem, Liu, Yuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841414/ https://www.ncbi.nlm.nih.gov/pubmed/36533524 http://dx.doi.org/10.1093/nar/gkac1178

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