Cargando…

Rapid single-molecule characterisation of enzymes involved in nucleic-acid metabolism

The activity of enzymes is traditionally characterised through bulk-phase biochemical methods that only report on population averages. Single-molecule methods are advantageous in elucidating kinetic and population heterogeneity but are often complicated, time consuming, and lack statistical power. W...

Descripción completa

Detalles Bibliográficos
Autores principales: Mueller, Stefan H, Fitschen, Lucy J, Shirbini, Afnan, Hamdan, Samir M, Spenkelink, Lisanne M, van Oijen, Antoine M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841422/
https://www.ncbi.nlm.nih.gov/pubmed/36321650
http://dx.doi.org/10.1093/nar/gkac949