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Rapid single-molecule characterisation of enzymes involved in nucleic-acid metabolism
The activity of enzymes is traditionally characterised through bulk-phase biochemical methods that only report on population averages. Single-molecule methods are advantageous in elucidating kinetic and population heterogeneity but are often complicated, time consuming, and lack statistical power. W...
Autores principales: | Mueller, Stefan H, Fitschen, Lucy J, Shirbini, Afnan, Hamdan, Samir M, Spenkelink, Lisanne M, van Oijen, Antoine M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9841422/ https://www.ncbi.nlm.nih.gov/pubmed/36321650 http://dx.doi.org/10.1093/nar/gkac949 |
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